Regulation of Wnt receptor activity: Implications for therapeutic development in colon cancer

Hyperactivation of Wnt/β-catenin (canonical) signaling in colorectal cancers (CRCs) was identified in the 1990s. Most CRC patients have mutations in genes that encode components of the Wnt pathway. Inactivating mutations in the adenomatous polyposis coli (APC) gene, which encodes a protein necessary...

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Detalles Bibliográficos
Autores principales: Zhong, Zhendong A., Michalski, Megan N., Stevens, Payton D., Sall, Emily A., Williams, Bart O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
JBC Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214085/
https://www.ncbi.nlm.nih.gov/pubmed/34000297
http://dx.doi.org/10.1016/j.jbc.2021.100782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214085/
https://www.ncbi.nlm.nih.gov/pubmed/34000297
http://dx.doi.org/10.1016/j.jbc.2021.100782

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