Adipose Triglyceride Lipase Loss Promotes a Metabolic Switch in A549 Non–Small Cell Lung Cancer Cell Spheroids

Cancer cells undergo complex metabolic adaptations to survive and thrive in challenging environments. This is particularly prominent for solid tumors, where cells in the core of the tumor are under severe hypoxia and nutrient deprivation. However, such conditions are often not recapitulated in the t...

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Detalles Bibliográficos
Autores principales: Honeder, Sophie, Tomin, Tamara, Nebel, Laura, Gindlhuber, Jürgen, Fritz-Wallace, Katarina, Schinagl, Maximilian, Heininger, Christoph, Schittmayer, Matthias, Ghaffari-Tabrizi-Wizsy, Nassim, Birner-Gruenberger, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214150/
https://www.ncbi.nlm.nih.gov/pubmed/33992777
http://dx.doi.org/10.1016/j.mcpro.2021.100095

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