Cargando…
Robustness of differential gene expression analysis of RNA-seq
RNA-sequencing (RNA-seq) is a relatively new technology that lacks standardisation. RNA-seq can be used for Differential Gene Expression (DGE) analysis, however, no consensus exists as to which methodology ensures robust and reproducible results. Indeed, it is broadly acknowledged that DGE methods p...
Autores principales: | Stupnikov, A., McInerney, C.E., Savage, K.I., McIntosh, S.A., Emmert-Streib, F., Kennedy, R., Salto-Tellez, M., Prise, K.M., McArt, D.G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214188/ https://www.ncbi.nlm.nih.gov/pubmed/34188784 http://dx.doi.org/10.1016/j.csbj.2021.05.040 |
Ejemplares similares
-
Impact of Variable RNA-Sequencing Depth on Gene Expression Signatures and Target Compound Robustness: Case Study Examining Brain Tumor (Glioma) Disease Progression
por: Stupnikov, Alexey, et al.
Publicado: (2018) -
Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches
por: Ellis, H. P., et al.
Publicado: (2019) -
Novel deep learning-based solution for identification of prognostic subgroups in liver cancer (Hepatocellular carcinoma)
por: Owens, Alice R., et al.
Publicado: (2021) -
Transcriptional Profiling of a Patient-Matched Cohort of Glioblastoma (IDH-Wildtype) for Therapeutic Target and Repurposing Drug Identification
por: Roddy, Aideen C., et al.
Publicado: (2023) -
Effects of subsampling on characteristics of RNA-seq data from triple-negative breast cancer patients
por: Stupnikov, Alexey, et al.
Publicado: (2015)