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Biliary excretion of excess iron in mice requires hepatocyte iron import by Slc39a14
Iron is essential for erythropoiesis and other biological processes, but is toxic in excess. Dietary absorption of iron is a highly regulated process and is a major determinant of body iron levels. Iron excretion, however, is considered a passive, unregulated process, and the underlying pathways are...
Autores principales: | Prajapati, Milankumar, Conboy, Heather L., Hojyo, Shintaro, Fukada, Toshiyuki, Budnik, Bogdan, Bartnikas, Thomas B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214222/ https://www.ncbi.nlm.nih.gov/pubmed/34051234 http://dx.doi.org/10.1016/j.jbc.2021.100835 |
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