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Enhanced HSC-like cell generation from mouse pluripotent stem cells in a 3D induction system cocultured with stromal cells

BACKGROUND: Decades of efforts have attempted to differentiate the pluripotent stem cells (PSCs) into truly functional hematopoietic stem cells (HSCs), yet the problems of low differentiation efficiency in vitro and poor hematopoiesis reconstitution in vivo still exist, mainly attributing to the lac...

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Detalles Bibliográficos
Autores principales:	Shan, Wei, Yu, Qin, Long, Yan, Luo, Qian, Li, Honghu, Han, Yingli, Xu, Yulin, Fu, Shan, Zeng, Xiangjun, Wei, Cong, Gao, Yang, Li, Xiaoqing, Li, Xia, Zhang, Lifei, Liu, Lizhen, Chen, Ming, Qian, Pengxu, Huang, He
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214308/ https://www.ncbi.nlm.nih.gov/pubmed/34147128 http://dx.doi.org/10.1186/s13287-021-02434-2

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