Giant Parathyroid Adenoma versus Parathyroid Carcinoma: Differentiating Two Entities

Giant parathyroid adenoma (GPA) is defined as adenoma larger than 3.5 g. Twenty-one cases of parathyroid mass >3.5 g in patients with primary hyperparathyroidism who underwent parathyroidectomy in Hospital Putrajaya, Malaysia were identified. Most cases presented with nephrolithiasis. Two cases a...

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Detalles Bibliográficos
Autores principales: Aziz, Hazwani, Hussein, Zanariah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the ASEAN Federation of Endocrine Societies 2021
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214351/
https://www.ncbi.nlm.nih.gov/pubmed/34177097
http://dx.doi.org/10.15605/jafes.036.01.11
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author Aziz, Hazwani
Hussein, Zanariah
author_facet Aziz, Hazwani
Hussein, Zanariah
author_sort Aziz, Hazwani
collection PubMed
description Giant parathyroid adenoma (GPA) is defined as adenoma larger than 3.5 g. Twenty-one cases of parathyroid mass >3.5 g in patients with primary hyperparathyroidism who underwent parathyroidectomy in Hospital Putrajaya, Malaysia were identified. Most cases presented with nephrolithiasis. Two cases are reported as parathyroid cancer. GPA has significantly higher serum calcium and iPTH levels and can be asymptomatic. Parathyroid carcinoma patients are frequently symptomatic, with large tumors. Differentiating GPA from parathyroid cancer is important as it determines the subsequent surgical intervention.
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spelling pubmed-82143512021-06-25 Giant Parathyroid Adenoma versus Parathyroid Carcinoma: Differentiating Two Entities Aziz, Hazwani Hussein, Zanariah J ASEAN Fed Endocr Soc Case Series Giant parathyroid adenoma (GPA) is defined as adenoma larger than 3.5 g. Twenty-one cases of parathyroid mass >3.5 g in patients with primary hyperparathyroidism who underwent parathyroidectomy in Hospital Putrajaya, Malaysia were identified. Most cases presented with nephrolithiasis. Two cases are reported as parathyroid cancer. GPA has significantly higher serum calcium and iPTH levels and can be asymptomatic. Parathyroid carcinoma patients are frequently symptomatic, with large tumors. Differentiating GPA from parathyroid cancer is important as it determines the subsequent surgical intervention. Journal of the ASEAN Federation of Endocrine Societies 2021-04-26 2021 /pmc/articles/PMC8214351/ /pubmed/34177097 http://dx.doi.org/10.15605/jafes.036.01.11 Text en © 2021 Journal of the ASEAN Federation of Endocrine Societies https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International.
spellingShingle Case Series
Aziz, Hazwani
Hussein, Zanariah
Giant Parathyroid Adenoma versus Parathyroid Carcinoma: Differentiating Two Entities
title Giant Parathyroid Adenoma versus Parathyroid Carcinoma: Differentiating Two Entities
title_full Giant Parathyroid Adenoma versus Parathyroid Carcinoma: Differentiating Two Entities
title_fullStr Giant Parathyroid Adenoma versus Parathyroid Carcinoma: Differentiating Two Entities
title_full_unstemmed Giant Parathyroid Adenoma versus Parathyroid Carcinoma: Differentiating Two Entities
title_short Giant Parathyroid Adenoma versus Parathyroid Carcinoma: Differentiating Two Entities
title_sort giant parathyroid adenoma versus parathyroid carcinoma: differentiating two entities
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214351/
https://www.ncbi.nlm.nih.gov/pubmed/34177097
http://dx.doi.org/10.15605/jafes.036.01.11
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