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Chidamide and Radiotherapy Synergistically Induce Cell Apoptosis and Suppress Tumor Growth and Cancer Stemness by Regulating the MiR-375-EIF4G3 Axis in Lung Squamous Cell Carcinomas

As a selective histone deacetylase (HDAC) inhibitor developed in China, chidamide has been applied for the treatment of refractory peripheral T-cell lymphoma (PTCL) and multiple solid tumors, including lung cancer. However, the underlying mechanisms are not well elucidated. In our present study, we...

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Detalles Bibliográficos
Autores principales: Huang, Xu, Bi, Nan, Wang, Jingbo, Ren, Hua, Pan, Desi, Lu, Xianping, Wang, Luhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214506/
https://www.ncbi.nlm.nih.gov/pubmed/34194495
http://dx.doi.org/10.1155/2021/4936207