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Deletion of SarX Decreases Biofilm Formation of Staphylococcus aureus in a Polysaccharide Intercellular Adhesin (PIA)-Dependent Manner by Downregulating spa

INTRODUCTION: Biofilm formation by Staphylococcus aureus is an important virulence determinant mediated by the polysaccharide intercellular adhesin (PIA) encoded by the ica operon or mediated by surface and extracellular proteins. SarX is a 250-residue two-domain SarA homolog that activates spa tran...

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Detalles Bibliográficos
Autores principales:	Hao, Zhihao, Guo, Yinjuan, Rao, Lulin, Yu, Jingyi, Zhan, Qing, Xu, Yanlei, Wang, Bingjie, Wu, Xiaocui, Yu, Fangyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214526/ https://www.ncbi.nlm.nih.gov/pubmed/34163189 http://dx.doi.org/10.2147/IDR.S305650

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