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Simultaneous Determination of Celecoxib, Dezocine and Dexmedetomidine in Beagle Plasma Using UPLC-MS/MS Method and the Application in Pharmacokinetics

BACKGROUND: An efficient, fast and sensitive ultra high-performance liquid chromatography-mass spectrometry (UPLC-MS/MS) method for simultaneous determination of celecoxib (CEL), dezocine (DEZ) and dexmedetomidine (DEX) in beagle plasma were established. METHODS: The beagle dogs plasmawas precipitat...

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Detalles Bibliográficos
Autores principales:	Hu, Jie, Su, Xin-juan, Si, Hui-Ling, Song, Rui-Xiang, Zhang, Fang, Qiu, Xiang-Jun, Chen, Xing-Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214532/ https://www.ncbi.nlm.nih.gov/pubmed/34163139 http://dx.doi.org/10.2147/DDDT.S314562

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