Cargando…

Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia

PURPOSE: Mid-upper arm circumference (MUAC) is a simple, noninvasive anthropometric indicator. This study evaluated the applicability of MUAC as an alternative screening instrument to appendicular skeletal muscle mass index (ASMI) for detecting sarcopenia, and determined the optimal MUAC cutoff valu...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Feng-Juan, Liu, Hu, Liu, Xiao-Lei, Jia, Shu-Li, Hou, Li-Sha, Xia, Xin, Dong, Bi-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214542/
https://www.ncbi.nlm.nih.gov/pubmed/34163153
http://dx.doi.org/10.2147/CIA.S311081
_version_ 1783710085683347456
author Hu, Feng-Juan
Liu, Hu
Liu, Xiao-Lei
Jia, Shu-Li
Hou, Li-Sha
Xia, Xin
Dong, Bi-Rong
author_facet Hu, Feng-Juan
Liu, Hu
Liu, Xiao-Lei
Jia, Shu-Li
Hou, Li-Sha
Xia, Xin
Dong, Bi-Rong
author_sort Hu, Feng-Juan
collection PubMed
description PURPOSE: Mid-upper arm circumference (MUAC) is a simple, noninvasive anthropometric indicator. This study evaluated the applicability of MUAC as an alternative screening instrument to appendicular skeletal muscle mass index (ASMI) for detecting sarcopenia, and determined the optimal MUAC cutoff values. PATIENTS AND METHODS: A total of 4509 subjects ≥50 years of age from the West China Health and Aging Trend study were included in the present study. ASM was measured by bioelectrical impedance analysis. MUAC, calf circumference (CC), and grip strength were evaluated and the Short Physical Performance Battery and 3-m timed up-and-go test were administered. Low muscle mass was diagnosed based on Asian Working Group for Sarcopenia 2019 (AWGS2019) and updated European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria. RESULTS: ASMI was positively correlated with MUAC in both men (r=0.726, P<0.001) and women (r=0.698, P<0.001). The area under the receiver operating characteristic curve (AUC) for MUAC as an indicator of low muscle mass in men and women was 0.86 (95% confidence interval [CI]: 0.85–0.88) and 0.85 (95% CI: 0.84–0.86), respectively, according to AWGS2019 criteria; and 0.86 (95% CI: 0.85–0.88) and 0.86 (95% CI: 0.85–0.88), respectively, according to EWGSOP2 criteria. Optimal MUAC cutoff values for predicting low muscle mass were ≤28.6 cm for men and ≤27.5 cm for women. There was no significant difference between the AUCs of MUAC and CC in men according to the 2 reference standards (P=0.809), whereas the AUC of CC was superior to that of MUAC in women according to AWGS2019 (P<0.001) and EWGSOP2 (P=0.008) criteria. CONCLUSION: MUAC is strongly correlated with ASMI among community-dwelling middle-aged and older adults in China. MUAC can be used as a simple screening instrument to ASMI for diagnosing sarcopenia, especially in men.
format Online
Article
Text
id pubmed-8214542
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-82145422021-06-22 Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia Hu, Feng-Juan Liu, Hu Liu, Xiao-Lei Jia, Shu-Li Hou, Li-Sha Xia, Xin Dong, Bi-Rong Clin Interv Aging Original Research PURPOSE: Mid-upper arm circumference (MUAC) is a simple, noninvasive anthropometric indicator. This study evaluated the applicability of MUAC as an alternative screening instrument to appendicular skeletal muscle mass index (ASMI) for detecting sarcopenia, and determined the optimal MUAC cutoff values. PATIENTS AND METHODS: A total of 4509 subjects ≥50 years of age from the West China Health and Aging Trend study were included in the present study. ASM was measured by bioelectrical impedance analysis. MUAC, calf circumference (CC), and grip strength were evaluated and the Short Physical Performance Battery and 3-m timed up-and-go test were administered. Low muscle mass was diagnosed based on Asian Working Group for Sarcopenia 2019 (AWGS2019) and updated European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria. RESULTS: ASMI was positively correlated with MUAC in both men (r=0.726, P<0.001) and women (r=0.698, P<0.001). The area under the receiver operating characteristic curve (AUC) for MUAC as an indicator of low muscle mass in men and women was 0.86 (95% confidence interval [CI]: 0.85–0.88) and 0.85 (95% CI: 0.84–0.86), respectively, according to AWGS2019 criteria; and 0.86 (95% CI: 0.85–0.88) and 0.86 (95% CI: 0.85–0.88), respectively, according to EWGSOP2 criteria. Optimal MUAC cutoff values for predicting low muscle mass were ≤28.6 cm for men and ≤27.5 cm for women. There was no significant difference between the AUCs of MUAC and CC in men according to the 2 reference standards (P=0.809), whereas the AUC of CC was superior to that of MUAC in women according to AWGS2019 (P<0.001) and EWGSOP2 (P=0.008) criteria. CONCLUSION: MUAC is strongly correlated with ASMI among community-dwelling middle-aged and older adults in China. MUAC can be used as a simple screening instrument to ASMI for diagnosing sarcopenia, especially in men. Dove 2021-06-15 /pmc/articles/PMC8214542/ /pubmed/34163153 http://dx.doi.org/10.2147/CIA.S311081 Text en © 2021 Hu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Hu, Feng-Juan
Liu, Hu
Liu, Xiao-Lei
Jia, Shu-Li
Hou, Li-Sha
Xia, Xin
Dong, Bi-Rong
Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
title Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
title_full Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
title_fullStr Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
title_full_unstemmed Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
title_short Mid-Upper Arm Circumference as an Alternative Screening Instrument to Appendicular Skeletal Muscle Mass Index for Diagnosing Sarcopenia
title_sort mid-upper arm circumference as an alternative screening instrument to appendicular skeletal muscle mass index for diagnosing sarcopenia
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214542/
https://www.ncbi.nlm.nih.gov/pubmed/34163153
http://dx.doi.org/10.2147/CIA.S311081
work_keys_str_mv AT hufengjuan midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia
AT liuhu midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia
AT liuxiaolei midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia
AT jiashuli midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia
AT houlisha midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia
AT xiaxin midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia
AT dongbirong midupperarmcircumferenceasanalternativescreeninginstrumenttoappendicularskeletalmusclemassindexfordiagnosingsarcopenia