Ticagrelor Use in Stroke Patients: Past, Present, and Future

Antiplatelet medications are the mainstay for secondary stroke treatment. Aspirin, clopidogrel, and aspirin-dipyridamole are commonly used antiplatelet medications. Other antiplatelet medications such as ticagrelor and prasugrel have been majorly used in cardiovascular or neuro-interventional specia...

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Autores principales: Chandra, Rahul, Saini, Harneel, Cerejo, Russell, Tayal, Ashis, Malhotra, Konark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214569/
https://www.ncbi.nlm.nih.gov/pubmed/34163168
http://dx.doi.org/10.2147/VHRM.S266968
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author Chandra, Rahul
Saini, Harneel
Cerejo, Russell
Tayal, Ashis
Malhotra, Konark
author_facet Chandra, Rahul
Saini, Harneel
Cerejo, Russell
Tayal, Ashis
Malhotra, Konark
author_sort Chandra, Rahul
collection PubMed
description Antiplatelet medications are the mainstay for secondary stroke treatment. Aspirin, clopidogrel, and aspirin-dipyridamole are commonly used antiplatelet medications. Other antiplatelet medications such as ticagrelor and prasugrel have been majorly used in cardiovascular or neuro-interventional specialties. Recent studies have paved a way to their use in secondary stroke prevention. In this review, we have briefly discussed the pharmacology of ticagrelor, published literature in cardiology and stroke trials, use of ticagrelor among patients with ischemic strokes, and compared its efficacy, limitations and side-effects with other antiplatelet medications.
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spelling pubmed-82145692021-06-22 Ticagrelor Use in Stroke Patients: Past, Present, and Future Chandra, Rahul Saini, Harneel Cerejo, Russell Tayal, Ashis Malhotra, Konark Vasc Health Risk Manag Review Antiplatelet medications are the mainstay for secondary stroke treatment. Aspirin, clopidogrel, and aspirin-dipyridamole are commonly used antiplatelet medications. Other antiplatelet medications such as ticagrelor and prasugrel have been majorly used in cardiovascular or neuro-interventional specialties. Recent studies have paved a way to their use in secondary stroke prevention. In this review, we have briefly discussed the pharmacology of ticagrelor, published literature in cardiology and stroke trials, use of ticagrelor among patients with ischemic strokes, and compared its efficacy, limitations and side-effects with other antiplatelet medications. Dove 2021-06-15 /pmc/articles/PMC8214569/ /pubmed/34163168 http://dx.doi.org/10.2147/VHRM.S266968 Text en © 2021 Chandra et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Chandra, Rahul
Saini, Harneel
Cerejo, Russell
Tayal, Ashis
Malhotra, Konark
Ticagrelor Use in Stroke Patients: Past, Present, and Future
title Ticagrelor Use in Stroke Patients: Past, Present, and Future
title_full Ticagrelor Use in Stroke Patients: Past, Present, and Future
title_fullStr Ticagrelor Use in Stroke Patients: Past, Present, and Future
title_full_unstemmed Ticagrelor Use in Stroke Patients: Past, Present, and Future
title_short Ticagrelor Use in Stroke Patients: Past, Present, and Future
title_sort ticagrelor use in stroke patients: past, present, and future
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214569/
https://www.ncbi.nlm.nih.gov/pubmed/34163168
http://dx.doi.org/10.2147/VHRM.S266968
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