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Rab11 is required for lysosome exocytosis through the interaction with Rab3a, Sec15 and GRAB
Lysosomes are dynamic organelles, capable of undergoing exocytosis. This process is crucial for several cellular functions, namely plasma membrane repair. Nevertheless, the molecular machinery involved in this process is poorly understood. Here, we identify Rab11a and Rab11b as regulators of Ca(2+)-...
Autores principales: | Escrevente, Cristina, Bento-Lopes, Liliana, Ramalho, José S., Barral, Duarte C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214760/ https://www.ncbi.nlm.nih.gov/pubmed/34100549 http://dx.doi.org/10.1242/jcs.246694 |
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