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Splenic Infarction with Aortic Thrombosis in COVID-19

Coronavirus disease 2019 (COVID-19) has been associated with an increased risk of venous and arterial thrombotic disease. Although pulmonary embolism has been the most common thrombotic complication, there have been recent reports of COVID-19-associated large-vessel ischemic stroke, acute upper- and...

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Autores principales: Sztajnbok, Jaques, Brasil, Lucas Mendes Cunha de Resende, Romero, Luis Arancibia, Ribeiro, Ana Freitas, Vidal, Jose Ernesto, Figueiredo-Mello, Claudia, Malaque, Ceila Maria Sant' Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Southern Society for Clinical Investigation. Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214812/
https://www.ncbi.nlm.nih.gov/pubmed/34161825
http://dx.doi.org/10.1016/j.amjms.2021.06.007
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author Sztajnbok, Jaques
Brasil, Lucas Mendes Cunha de Resende
Romero, Luis Arancibia
Ribeiro, Ana Freitas
Vidal, Jose Ernesto
Figueiredo-Mello, Claudia
Malaque, Ceila Maria Sant' Ana
author_facet Sztajnbok, Jaques
Brasil, Lucas Mendes Cunha de Resende
Romero, Luis Arancibia
Ribeiro, Ana Freitas
Vidal, Jose Ernesto
Figueiredo-Mello, Claudia
Malaque, Ceila Maria Sant' Ana
author_sort Sztajnbok, Jaques
collection PubMed
description Coronavirus disease 2019 (COVID-19) has been associated with an increased risk of venous and arterial thrombotic disease. Although pulmonary embolism has been the most common thrombotic complication, there have been recent reports of COVID-19-associated large-vessel ischemic stroke, acute upper- and lower-limb ischemia, as well as infarctions of the abdominal viscera, including renal, splenic, and small bowel infarctions. Here, we describe a case of splenic infarction (SI) associated with aortic thrombosis, which evolved despite the prophylactic use of low-molecular-weight heparin (LMWH), in a 60-year-old female patient with COVID-19. The patient was treated clinically with a therapeutic dose of LMWH, followed by warfarin, and eventually presented a favorable outcome. We also present a review of the literature regarding SI in patients with COVID-19.
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spelling pubmed-82148122021-06-21 Splenic Infarction with Aortic Thrombosis in COVID-19 Sztajnbok, Jaques Brasil, Lucas Mendes Cunha de Resende Romero, Luis Arancibia Ribeiro, Ana Freitas Vidal, Jose Ernesto Figueiredo-Mello, Claudia Malaque, Ceila Maria Sant' Ana Am J Med Sci Special Feature Coronavirus disease 2019 (COVID-19) has been associated with an increased risk of venous and arterial thrombotic disease. Although pulmonary embolism has been the most common thrombotic complication, there have been recent reports of COVID-19-associated large-vessel ischemic stroke, acute upper- and lower-limb ischemia, as well as infarctions of the abdominal viscera, including renal, splenic, and small bowel infarctions. Here, we describe a case of splenic infarction (SI) associated with aortic thrombosis, which evolved despite the prophylactic use of low-molecular-weight heparin (LMWH), in a 60-year-old female patient with COVID-19. The patient was treated clinically with a therapeutic dose of LMWH, followed by warfarin, and eventually presented a favorable outcome. We also present a review of the literature regarding SI in patients with COVID-19. Southern Society for Clinical Investigation. Published by Elsevier Inc. 2021-10 2021-06-20 /pmc/articles/PMC8214812/ /pubmed/34161825 http://dx.doi.org/10.1016/j.amjms.2021.06.007 Text en © 2021 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Special Feature
Sztajnbok, Jaques
Brasil, Lucas Mendes Cunha de Resende
Romero, Luis Arancibia
Ribeiro, Ana Freitas
Vidal, Jose Ernesto
Figueiredo-Mello, Claudia
Malaque, Ceila Maria Sant' Ana
Splenic Infarction with Aortic Thrombosis in COVID-19
title Splenic Infarction with Aortic Thrombosis in COVID-19
title_full Splenic Infarction with Aortic Thrombosis in COVID-19
title_fullStr Splenic Infarction with Aortic Thrombosis in COVID-19
title_full_unstemmed Splenic Infarction with Aortic Thrombosis in COVID-19
title_short Splenic Infarction with Aortic Thrombosis in COVID-19
title_sort splenic infarction with aortic thrombosis in covid-19
topic Special Feature
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214812/
https://www.ncbi.nlm.nih.gov/pubmed/34161825
http://dx.doi.org/10.1016/j.amjms.2021.06.007
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