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Splenic Infarction with Aortic Thrombosis in COVID-19
Coronavirus disease 2019 (COVID-19) has been associated with an increased risk of venous and arterial thrombotic disease. Although pulmonary embolism has been the most common thrombotic complication, there have been recent reports of COVID-19-associated large-vessel ischemic stroke, acute upper- and...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Southern Society for Clinical Investigation. Published by Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214812/ https://www.ncbi.nlm.nih.gov/pubmed/34161825 http://dx.doi.org/10.1016/j.amjms.2021.06.007 |
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author | Sztajnbok, Jaques Brasil, Lucas Mendes Cunha de Resende Romero, Luis Arancibia Ribeiro, Ana Freitas Vidal, Jose Ernesto Figueiredo-Mello, Claudia Malaque, Ceila Maria Sant' Ana |
author_facet | Sztajnbok, Jaques Brasil, Lucas Mendes Cunha de Resende Romero, Luis Arancibia Ribeiro, Ana Freitas Vidal, Jose Ernesto Figueiredo-Mello, Claudia Malaque, Ceila Maria Sant' Ana |
author_sort | Sztajnbok, Jaques |
collection | PubMed |
description | Coronavirus disease 2019 (COVID-19) has been associated with an increased risk of venous and arterial thrombotic disease. Although pulmonary embolism has been the most common thrombotic complication, there have been recent reports of COVID-19-associated large-vessel ischemic stroke, acute upper- and lower-limb ischemia, as well as infarctions of the abdominal viscera, including renal, splenic, and small bowel infarctions. Here, we describe a case of splenic infarction (SI) associated with aortic thrombosis, which evolved despite the prophylactic use of low-molecular-weight heparin (LMWH), in a 60-year-old female patient with COVID-19. The patient was treated clinically with a therapeutic dose of LMWH, followed by warfarin, and eventually presented a favorable outcome. We also present a review of the literature regarding SI in patients with COVID-19. |
format | Online Article Text |
id | pubmed-8214812 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Southern Society for Clinical Investigation. Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82148122021-06-21 Splenic Infarction with Aortic Thrombosis in COVID-19 Sztajnbok, Jaques Brasil, Lucas Mendes Cunha de Resende Romero, Luis Arancibia Ribeiro, Ana Freitas Vidal, Jose Ernesto Figueiredo-Mello, Claudia Malaque, Ceila Maria Sant' Ana Am J Med Sci Special Feature Coronavirus disease 2019 (COVID-19) has been associated with an increased risk of venous and arterial thrombotic disease. Although pulmonary embolism has been the most common thrombotic complication, there have been recent reports of COVID-19-associated large-vessel ischemic stroke, acute upper- and lower-limb ischemia, as well as infarctions of the abdominal viscera, including renal, splenic, and small bowel infarctions. Here, we describe a case of splenic infarction (SI) associated with aortic thrombosis, which evolved despite the prophylactic use of low-molecular-weight heparin (LMWH), in a 60-year-old female patient with COVID-19. The patient was treated clinically with a therapeutic dose of LMWH, followed by warfarin, and eventually presented a favorable outcome. We also present a review of the literature regarding SI in patients with COVID-19. Southern Society for Clinical Investigation. Published by Elsevier Inc. 2021-10 2021-06-20 /pmc/articles/PMC8214812/ /pubmed/34161825 http://dx.doi.org/10.1016/j.amjms.2021.06.007 Text en © 2021 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Special Feature Sztajnbok, Jaques Brasil, Lucas Mendes Cunha de Resende Romero, Luis Arancibia Ribeiro, Ana Freitas Vidal, Jose Ernesto Figueiredo-Mello, Claudia Malaque, Ceila Maria Sant' Ana Splenic Infarction with Aortic Thrombosis in COVID-19 |
title | Splenic Infarction with Aortic Thrombosis in COVID-19 |
title_full | Splenic Infarction with Aortic Thrombosis in COVID-19 |
title_fullStr | Splenic Infarction with Aortic Thrombosis in COVID-19 |
title_full_unstemmed | Splenic Infarction with Aortic Thrombosis in COVID-19 |
title_short | Splenic Infarction with Aortic Thrombosis in COVID-19 |
title_sort | splenic infarction with aortic thrombosis in covid-19 |
topic | Special Feature |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214812/ https://www.ncbi.nlm.nih.gov/pubmed/34161825 http://dx.doi.org/10.1016/j.amjms.2021.06.007 |
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