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Antibacterial mechanism of Cu-bearing 430 ferritic stainless steel

Copper (Cu)-bearing stainless steel has testified its effectiveness to reduce the risk of bacterial infections. However, its antibacterial mechanism is still controversial. Therefore, three 430 ferritic stainless steels with different Cu contents are selected to conduct deeper research by the way of...

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Autores principales: Zhang, Zhuang, Zhang, Xin-Rui, Jin , Tao, Yang, Chun-Guang, Sun, Yu-Peng, Li, Qi, Yang, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nonferrous Metals Society of China 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214840/
https://www.ncbi.nlm.nih.gov/pubmed/34177195
http://dx.doi.org/10.1007/s12598-021-01751-y
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author Zhang, Zhuang
Zhang, Xin-Rui
Jin , Tao
Yang, Chun-Guang
Sun, Yu-Peng
Li, Qi
Yang, Ke
author_facet Zhang, Zhuang
Zhang, Xin-Rui
Jin , Tao
Yang, Chun-Guang
Sun, Yu-Peng
Li, Qi
Yang, Ke
author_sort Zhang, Zhuang
collection PubMed
description Copper (Cu)-bearing stainless steel has testified its effectiveness to reduce the risk of bacterial infections. However, its antibacterial mechanism is still controversial. Therefore, three 430 ferritic stainless steels with different Cu contents are selected to conduct deeper research by the way of bacterial inactivation from two aspects of material and biology. Hereinto, electrochemical and antibacterial results show that the increase in Cu content simultaneously improves the corrosion resistance and antibacterial property of 430 stainless steel. In addition, it is found that Escherichia coli (E. coli) on the surface 430 Cu-bearing stainless steel by the dry method of inoculation possesses a rapid inactivation ability. X-ray photoelectron spectroscopy (XPS) aids with ion chelation experiments prove that Cu (I) plays a more crucial role in the contact-killing efficiency than Cu (II), resulting from more production of reactive oxygen species (ROS). GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-82148402021-06-21 Antibacterial mechanism of Cu-bearing 430 ferritic stainless steel Zhang, Zhuang Zhang, Xin-Rui Jin , Tao Yang, Chun-Guang Sun, Yu-Peng Li, Qi Yang, Ke Rare Metals Original Article Copper (Cu)-bearing stainless steel has testified its effectiveness to reduce the risk of bacterial infections. However, its antibacterial mechanism is still controversial. Therefore, three 430 ferritic stainless steels with different Cu contents are selected to conduct deeper research by the way of bacterial inactivation from two aspects of material and biology. Hereinto, electrochemical and antibacterial results show that the increase in Cu content simultaneously improves the corrosion resistance and antibacterial property of 430 stainless steel. In addition, it is found that Escherichia coli (E. coli) on the surface 430 Cu-bearing stainless steel by the dry method of inoculation possesses a rapid inactivation ability. X-ray photoelectron spectroscopy (XPS) aids with ion chelation experiments prove that Cu (I) plays a more crucial role in the contact-killing efficiency than Cu (II), resulting from more production of reactive oxygen species (ROS). GRAPHICAL ABSTRACT: [Image: see text] Nonferrous Metals Society of China 2021-06-20 2022 /pmc/articles/PMC8214840/ /pubmed/34177195 http://dx.doi.org/10.1007/s12598-021-01751-y Text en © Youke Publishing Co.,Ltd 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Article
Zhang, Zhuang
Zhang, Xin-Rui
Jin , Tao
Yang, Chun-Guang
Sun, Yu-Peng
Li, Qi
Yang, Ke
Antibacterial mechanism of Cu-bearing 430 ferritic stainless steel
title Antibacterial mechanism of Cu-bearing 430 ferritic stainless steel
title_full Antibacterial mechanism of Cu-bearing 430 ferritic stainless steel
title_fullStr Antibacterial mechanism of Cu-bearing 430 ferritic stainless steel
title_full_unstemmed Antibacterial mechanism of Cu-bearing 430 ferritic stainless steel
title_short Antibacterial mechanism of Cu-bearing 430 ferritic stainless steel
title_sort antibacterial mechanism of cu-bearing 430 ferritic stainless steel
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214840/
https://www.ncbi.nlm.nih.gov/pubmed/34177195
http://dx.doi.org/10.1007/s12598-021-01751-y
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