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Acute Kidney Injury in Transcatheter Aortic Valve Replacement
Introduction Transcatheter aortic valve replacement (TAVR) has been established as a standard of care for patients with severe aortic stenosis. We aim to study the predictors of acute kidney injury (AKI) after TAVR from a contemporary analysis using the National Inpatient Sample (NIS) database. Meth...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214866/ https://www.ncbi.nlm.nih.gov/pubmed/34168922 http://dx.doi.org/10.7759/cureus.15154 |
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author | Abbas, Sakina Qayum, Ihtisham Wahid, Rabiya Salman, FNU Khan, Henna Hassan, Fatima Babar, Anum Inayat, Arslan |
author_facet | Abbas, Sakina Qayum, Ihtisham Wahid, Rabiya Salman, FNU Khan, Henna Hassan, Fatima Babar, Anum Inayat, Arslan |
author_sort | Abbas, Sakina |
collection | PubMed |
description | Introduction Transcatheter aortic valve replacement (TAVR) has been established as a standard of care for patients with severe aortic stenosis. We aim to study the predictors of acute kidney injury (AKI) after TAVR from a contemporary analysis using the National Inpatient Sample (NIS) database. Methods We performed a national analysis using the NIS database to evaluate predictors of acute kidney injury (AKI) after TAVR. Our study period was from 2015 to 2018, and we identified TAVR patients in all procedure fields. Patients aged less than 18 years were excluded from the study. Results We report data of 173,760 TAVR patients, of which 20,045 (11.5%) had AKI and 153,715 (88.4%) did not. There were three principal findings of our study. First, mortality was higher in patients with AKI compared to patients who did not have AKI (8% vs. 0.8%; p<0.01). Second, patients with chronic kidney disease, weight loss, liver disease, congestive heart failure, cerebrovascular disease, chronic obstructive pulmonary disease, metastatic cancer, and peripheral vascular disease had higher adjusted odds of AKI. Third, length of stay and cost of stay were significantly higher in patients who had AKI during the index admission. Conclusion Patients with AKI had higher in-hospital mortality. We also report that at baseline, chronic kidney disease, weight loss, liver disease, congestive heart failure, cerebrovascular disease, chronic obstructive pulmonary disease, metastatic cancer, and peripheral vascular disease were important predictors of AKI in patients after TAVR. Length of stay and cost of stay were higher with AKI, which result in higher burden on the health care system due to increased resource utilization. |
format | Online Article Text |
id | pubmed-8214866 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-82148662021-06-23 Acute Kidney Injury in Transcatheter Aortic Valve Replacement Abbas, Sakina Qayum, Ihtisham Wahid, Rabiya Salman, FNU Khan, Henna Hassan, Fatima Babar, Anum Inayat, Arslan Cureus Cardiac/Thoracic/Vascular Surgery Introduction Transcatheter aortic valve replacement (TAVR) has been established as a standard of care for patients with severe aortic stenosis. We aim to study the predictors of acute kidney injury (AKI) after TAVR from a contemporary analysis using the National Inpatient Sample (NIS) database. Methods We performed a national analysis using the NIS database to evaluate predictors of acute kidney injury (AKI) after TAVR. Our study period was from 2015 to 2018, and we identified TAVR patients in all procedure fields. Patients aged less than 18 years were excluded from the study. Results We report data of 173,760 TAVR patients, of which 20,045 (11.5%) had AKI and 153,715 (88.4%) did not. There were three principal findings of our study. First, mortality was higher in patients with AKI compared to patients who did not have AKI (8% vs. 0.8%; p<0.01). Second, patients with chronic kidney disease, weight loss, liver disease, congestive heart failure, cerebrovascular disease, chronic obstructive pulmonary disease, metastatic cancer, and peripheral vascular disease had higher adjusted odds of AKI. Third, length of stay and cost of stay were significantly higher in patients who had AKI during the index admission. Conclusion Patients with AKI had higher in-hospital mortality. We also report that at baseline, chronic kidney disease, weight loss, liver disease, congestive heart failure, cerebrovascular disease, chronic obstructive pulmonary disease, metastatic cancer, and peripheral vascular disease were important predictors of AKI in patients after TAVR. Length of stay and cost of stay were higher with AKI, which result in higher burden on the health care system due to increased resource utilization. Cureus 2021-05-21 /pmc/articles/PMC8214866/ /pubmed/34168922 http://dx.doi.org/10.7759/cureus.15154 Text en Copyright © 2021, Abbas et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiac/Thoracic/Vascular Surgery Abbas, Sakina Qayum, Ihtisham Wahid, Rabiya Salman, FNU Khan, Henna Hassan, Fatima Babar, Anum Inayat, Arslan Acute Kidney Injury in Transcatheter Aortic Valve Replacement |
title | Acute Kidney Injury in Transcatheter Aortic Valve Replacement |
title_full | Acute Kidney Injury in Transcatheter Aortic Valve Replacement |
title_fullStr | Acute Kidney Injury in Transcatheter Aortic Valve Replacement |
title_full_unstemmed | Acute Kidney Injury in Transcatheter Aortic Valve Replacement |
title_short | Acute Kidney Injury in Transcatheter Aortic Valve Replacement |
title_sort | acute kidney injury in transcatheter aortic valve replacement |
topic | Cardiac/Thoracic/Vascular Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214866/ https://www.ncbi.nlm.nih.gov/pubmed/34168922 http://dx.doi.org/10.7759/cureus.15154 |
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