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Pseudomonas aeruginosa necrotizing bronchopneumonia

Extremely low birth weight (ELBW) infants are at particularly high risk for infection due to an immature immune system, invasive procedures such as endotracheal intubation, intravascular catheterization, and other factors. Neonatal infections in this population are associated with a high mortality,...

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Autor principal: Kylat, Ranjit I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital Universitário da Universidade de São Paulo 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214876/
https://www.ncbi.nlm.nih.gov/pubmed/34307227
http://dx.doi.org/10.4322/acr.2021.271
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author Kylat, Ranjit I
author_facet Kylat, Ranjit I
author_sort Kylat, Ranjit I
collection PubMed
description Extremely low birth weight (ELBW) infants are at particularly high risk for infection due to an immature immune system, invasive procedures such as endotracheal intubation, intravascular catheterization, and other factors. Neonatal infections in this population are associated with a high mortality, poor growth, and neurodevelopmental outcomes. Pseudomonas aeruginosa (P. aeruginosa) infection is an uncommon but potentially devastating cause of pneumonia and sepsis in the ELBW population. P. aeruginosa is an important cause of healthcare-associated infections (HAI) or nosocomial infections. P. aeruginosa can perceive unfavorable environmental changes and orchestrate adaptations by developing plasmid-mediated and adaptive resistance to antibiotics. We describe an ELBW infant born at 26 weeks’ gestation who succumbed at 13 days of life to P. aeruginosa infection. Some of the factors related to the pathogenesis and multidrug resistance are described.
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spelling pubmed-82148762021-07-23 Pseudomonas aeruginosa necrotizing bronchopneumonia Kylat, Ranjit I Autops Case Rep Autopsy Case Report Extremely low birth weight (ELBW) infants are at particularly high risk for infection due to an immature immune system, invasive procedures such as endotracheal intubation, intravascular catheterization, and other factors. Neonatal infections in this population are associated with a high mortality, poor growth, and neurodevelopmental outcomes. Pseudomonas aeruginosa (P. aeruginosa) infection is an uncommon but potentially devastating cause of pneumonia and sepsis in the ELBW population. P. aeruginosa is an important cause of healthcare-associated infections (HAI) or nosocomial infections. P. aeruginosa can perceive unfavorable environmental changes and orchestrate adaptations by developing plasmid-mediated and adaptive resistance to antibiotics. We describe an ELBW infant born at 26 weeks’ gestation who succumbed at 13 days of life to P. aeruginosa infection. Some of the factors related to the pathogenesis and multidrug resistance are described. Hospital Universitário da Universidade de São Paulo 2021-05-06 /pmc/articles/PMC8214876/ /pubmed/34307227 http://dx.doi.org/10.4322/acr.2021.271 Text en Copyright © 2021 The Authors. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Autopsy Case Report
Kylat, Ranjit I
Pseudomonas aeruginosa necrotizing bronchopneumonia
title Pseudomonas aeruginosa necrotizing bronchopneumonia
title_full Pseudomonas aeruginosa necrotizing bronchopneumonia
title_fullStr Pseudomonas aeruginosa necrotizing bronchopneumonia
title_full_unstemmed Pseudomonas aeruginosa necrotizing bronchopneumonia
title_short Pseudomonas aeruginosa necrotizing bronchopneumonia
title_sort pseudomonas aeruginosa necrotizing bronchopneumonia
topic Autopsy Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214876/
https://www.ncbi.nlm.nih.gov/pubmed/34307227
http://dx.doi.org/10.4322/acr.2021.271
work_keys_str_mv AT kylatranjiti pseudomonasaeruginosanecrotizingbronchopneumonia