Primary malignant giant cell tumor of the sternum

Primary malignant giant cell tumor (PMGCT) is a diagnosis based on the presence of a high-grade sarcomatous component along with a typical benign giant cell tumor (GCT). We report the first case of PMGCT of the sternum in a 28-year-old male with painless swelling over the manubrium sterni. The diffe...

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Autores principales: Imaduddin, Mohammed, Ayyanar, Pavithra, Sultania, Mahesh, Muduly, Dillip, Sable, Mukund Namdev, Naik, Suprava, Mohanty, Sambit, Kar, Madhabananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital Universitário da Universidade de São Paulo 2021
Materias:
Clinical Case Report and Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214899/
https://www.ncbi.nlm.nih.gov/pubmed/34249788
http://dx.doi.org/10.4322/acr.2021.281
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author Imaduddin, Mohammed
Ayyanar, Pavithra
Sultania, Mahesh
Muduly, Dillip
Sable, Mukund Namdev
Naik, Suprava
Mohanty, Sambit
Kar, Madhabananda
author_facet Imaduddin, Mohammed
Ayyanar, Pavithra
Sultania, Mahesh
Muduly, Dillip
Sable, Mukund Namdev
Naik, Suprava
Mohanty, Sambit
Kar, Madhabananda
author_sort Imaduddin, Mohammed
collection PubMed
description Primary malignant giant cell tumor (PMGCT) is a diagnosis based on the presence of a high-grade sarcomatous component along with a typical benign giant cell tumor (GCT). We report the first case of PMGCT of the sternum in a 28-year-old male with painless swelling over the manubrium sterni. The differential diagnoses of PMGCT and giant cell-rich osteosarcoma were considered. Surgical resection was performed, and the reconstruction was done with a neosternum using polymethyl methacrylate and prolene mesh. At 30 months follow-up, the patient is disease-free.
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spelling pubmed-82148992021-07-09 Primary malignant giant cell tumor of the sternum Imaduddin, Mohammed Ayyanar, Pavithra Sultania, Mahesh Muduly, Dillip Sable, Mukund Namdev Naik, Suprava Mohanty, Sambit Kar, Madhabananda Autops Case Rep Clinical Case Report and Review Primary malignant giant cell tumor (PMGCT) is a diagnosis based on the presence of a high-grade sarcomatous component along with a typical benign giant cell tumor (GCT). We report the first case of PMGCT of the sternum in a 28-year-old male with painless swelling over the manubrium sterni. The differential diagnoses of PMGCT and giant cell-rich osteosarcoma were considered. Surgical resection was performed, and the reconstruction was done with a neosternum using polymethyl methacrylate and prolene mesh. At 30 months follow-up, the patient is disease-free. Hospital Universitário da Universidade de São Paulo 2021-05-25 /pmc/articles/PMC8214899/ /pubmed/34249788 http://dx.doi.org/10.4322/acr.2021.281 Text en Copyright: © 2021 The Authors. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Case Report and Review
Imaduddin, Mohammed
Ayyanar, Pavithra
Sultania, Mahesh
Muduly, Dillip
Sable, Mukund Namdev
Naik, Suprava
Mohanty, Sambit
Kar, Madhabananda
Primary malignant giant cell tumor of the sternum
title Primary malignant giant cell tumor of the sternum
title_full Primary malignant giant cell tumor of the sternum
title_fullStr Primary malignant giant cell tumor of the sternum
title_full_unstemmed Primary malignant giant cell tumor of the sternum
title_short Primary malignant giant cell tumor of the sternum
title_sort primary malignant giant cell tumor of the sternum
topic Clinical Case Report and Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214899/
https://www.ncbi.nlm.nih.gov/pubmed/34249788
http://dx.doi.org/10.4322/acr.2021.281
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