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Invasive pulmonary aspergillosis with brain dissemination in an immunocompetent host
Invasive aspergillosis is an uncommon infection, which is mainly seen among immunocompromised patients. In recent years, cases of aspergillosis involving immunocompetent hosts are increasingly being reported. Herein, we report the case of a 27-year-old man with fever, productive cough, shortness of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hospital Universitário da Universidade de São Paulo
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214902/ https://www.ncbi.nlm.nih.gov/pubmed/34307233 http://dx.doi.org/10.4322/acr.2021.280 |
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author | Kumar, Senthil Muthu, Valliappan Bansal, Yogender Singh Mehta, Nikhil Arora, Vanshika |
author_facet | Kumar, Senthil Muthu, Valliappan Bansal, Yogender Singh Mehta, Nikhil Arora, Vanshika |
author_sort | Kumar, Senthil |
collection | PubMed |
description | Invasive aspergillosis is an uncommon infection, which is mainly seen among immunocompromised patients. In recent years, cases of aspergillosis involving immunocompetent hosts are increasingly being reported. Herein, we report the case of a 27-year-old man with fever, productive cough, shortness of breath, and left hemiparesis. He had suffered trauma to his head 25 days prior. Imaging of the chest showed bilateral cavitary lesions in the lungs, and neuroimaging revealed a space-occupying lesion in the right frontoparietal cerebrum. He was suspected of having an abscess or metastasis. He died on day 3 of hospitalization, and an autopsy was performed. The autopsy revealed the cause of death to be invasive pulmonary aspergillosis, with brain dissemination. Invasive aspergillosis is uncommon in apparently immunocompetent individuals, and we discuss the autopsy findings in detail. |
format | Online Article Text |
id | pubmed-8214902 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hospital Universitário da Universidade de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-82149022021-07-23 Invasive pulmonary aspergillosis with brain dissemination in an immunocompetent host Kumar, Senthil Muthu, Valliappan Bansal, Yogender Singh Mehta, Nikhil Arora, Vanshika Autops Case Rep Autopsy Case Report Invasive aspergillosis is an uncommon infection, which is mainly seen among immunocompromised patients. In recent years, cases of aspergillosis involving immunocompetent hosts are increasingly being reported. Herein, we report the case of a 27-year-old man with fever, productive cough, shortness of breath, and left hemiparesis. He had suffered trauma to his head 25 days prior. Imaging of the chest showed bilateral cavitary lesions in the lungs, and neuroimaging revealed a space-occupying lesion in the right frontoparietal cerebrum. He was suspected of having an abscess or metastasis. He died on day 3 of hospitalization, and an autopsy was performed. The autopsy revealed the cause of death to be invasive pulmonary aspergillosis, with brain dissemination. Invasive aspergillosis is uncommon in apparently immunocompetent individuals, and we discuss the autopsy findings in detail. Hospital Universitário da Universidade de São Paulo 2021-05-06 /pmc/articles/PMC8214902/ /pubmed/34307233 http://dx.doi.org/10.4322/acr.2021.280 Text en Copyright: © 2021 The Authors. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Autopsy Case Report Kumar, Senthil Muthu, Valliappan Bansal, Yogender Singh Mehta, Nikhil Arora, Vanshika Invasive pulmonary aspergillosis with brain dissemination in an immunocompetent host |
title | Invasive pulmonary aspergillosis with brain dissemination in an immunocompetent host |
title_full | Invasive pulmonary aspergillosis with brain dissemination in an immunocompetent host |
title_fullStr | Invasive pulmonary aspergillosis with brain dissemination in an immunocompetent host |
title_full_unstemmed | Invasive pulmonary aspergillosis with brain dissemination in an immunocompetent host |
title_short | Invasive pulmonary aspergillosis with brain dissemination in an immunocompetent host |
title_sort | invasive pulmonary aspergillosis with brain dissemination in an immunocompetent host |
topic | Autopsy Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214902/ https://www.ncbi.nlm.nih.gov/pubmed/34307233 http://dx.doi.org/10.4322/acr.2021.280 |
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