Cargando…

Persistent cognitive impairment associated with cerebrospinal fluid anti-SARS-CoV-2 antibodies six months after mild COVID-19

Neurological long-term sequelae are increasingly considered an important challenge in the recent COVID-19 pandemic. However, most evidence for neurological symptoms after SARS-CoV-2 infection and central nervous system invasion of the virus stems from individuals severely affected in the acute phase...

Descripción completa

Detalles Bibliográficos
Autores principales: Borsche, Max, Reichel, Dirk, Fellbrich, Anja, Lixenfeld, Anne S., Rahmöller, Johann, Vollstedt, Eva-Juliane, Föh, Bandik, Balck, Alexander, Klein, Christine, Ehlers, Marc, Moser, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214919/
https://www.ncbi.nlm.nih.gov/pubmed/34148546
http://dx.doi.org/10.1186/s42466-021-00135-y
Descripción
Sumario:Neurological long-term sequelae are increasingly considered an important challenge in the recent COVID-19 pandemic. However, most evidence for neurological symptoms after SARS-CoV-2 infection and central nervous system invasion of the virus stems from individuals severely affected in the acute phase of the disease. Here, we report long-lasting cognitive impairment along with persistent cerebrospinal fluid anti-SARS-CoV-2 antibodies in a female patient with unremarkable standard examination 6 months after mild COVID-19, supporting the implementation of neuropsychological testing and specific cerebrospinal fluid investigation also in patients with a relatively mild acute disease phase. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s42466-021-00135-y.