Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation

Growth differentiation factor 15 (GDF15) causes anorexia and weight loss in animal models, and higher circulating levels are associated with cachexia and reduced survival in cancer and other chronic diseases such as sepsis. To investigate the role of sepsis-induced GDF15, we examined whether GDF15 n...

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Detalles Bibliográficos
Autores principales: Breen, Danna M., Jagarlapudi, Srinath, Patel, Anita, Zou, Chang, Joaquim, Stephanie, Li, Xiangping, Kang, Liya, Pang, Jincheng, Hales, Katherine, Ziso-Qejvanaj, Enida, Vera, Nicholas B., Bennett, Donald, He, Tao, Lambert, Matthew, Kelleher, Kerry, Wu, Zhidan, Zhang, Bei B., Lin, Laura, Seeley, Randy J., Bezy, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215224/
https://www.ncbi.nlm.nih.gov/pubmed/34189431
http://dx.doi.org/10.1016/j.isci.2021.102554

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