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S100A4 enhances protumor macrophage polarization by control of PPAR-γ-dependent induction of fatty acid oxidation

BACKGROUND: The peroxisome proliferator-activated receptor γ (PPAR-γ)-dependent upregulation of fatty acid oxidation (FAO) mediates protumor (also known as M2-like) polarization of tumor-associated macrophages (TAMs). However, upstream factors determining PPAR-γ upregulation in TAM protumor polariza...

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Detalles Bibliográficos
Autores principales: Liu, Shuangqing, Zhang, Huilei, Li, Yanan, Zhang, Yana, Bian, Yangyang, Zeng, Yanqiong, Yao, Xiaohan, Wan, Jiajia, Chen, Xu, Li, Jianru, Wang, Zhaoqing, Qin, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215236/
https://www.ncbi.nlm.nih.gov/pubmed/34145030
http://dx.doi.org/10.1136/jitc-2021-002548