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A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion

Guided by a multi-level “deconstruction” of omental metastases, we developed a tetra (four cell)-culture model of primary human mesothelial cells, fibroblasts, adipocytes, and high-grade serous ovarian cancer (HGSOC) cell lines. This multi-cellular model replicated key elements of human metastases a...

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Detalles Bibliográficos
Autores principales:	Malacrida, Beatrice, Nichols, Sam, Maniati, Eleni, Jones, Roanne, Delanie-Smith, Robin, Roozitalab, Reza, Tyler, Eleanor J., Thomas, Morgan, Boot, Gina, Mackerodt, Jonas, Lockley, Michelle, Knight, Martin M., Balkwill, Frances R., Pearce, Oliver M.T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215303/ https://www.ncbi.nlm.nih.gov/pubmed/34189439 http://dx.doi.org/10.1016/j.isci.2021.102676

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