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Neddylation Regulates Macrophages and Implications for Cancer Therapy

Tumor-associated macrophages (TAMs) promote cancer progression via stimulating angiogenesis, invasion/metastasis, and suppressing anti-cancer immunity. Targeting TAMs is a potential promising cancer therapeutic strategy. Neddylation adds the ubiquitin-like protein NEDD8 to substrates, and thereby re...

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Detalles Bibliográficos
Autores principales:	Jiang, Yanyu, Li, Lihui, Li, Yan, Liu, Guangwei, Hoffman, Robert M., Jia, Lijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215544/ https://www.ncbi.nlm.nih.gov/pubmed/34164400 http://dx.doi.org/10.3389/fcell.2021.681186

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