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Drug Delivery Systems for Hedgehog Inhibitors in the Treatment of SHH-Medulloblastoma
Medulloblastoma (MB) is a highly aggressive pediatric tumor of the cerebellum. Hyperactivation of the Hedgehog (HH) pathway is observed in about 30% of all MB diagnoses, thereby bringing out its pharmacological blockade as a promising therapeutic strategy for the clinical management of this malignan...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215655/ https://www.ncbi.nlm.nih.gov/pubmed/34164380 http://dx.doi.org/10.3389/fchem.2021.688108 |