Cargando…

Roflumilast Suppresses Adipogenic Differentiation via AMPK Mediated Pathway

Obesity and related disorders have increasingly become global health problems over the years. In recent years, obesity has been recognized as the most important risk factor for a variety of diseases including cardiovascular diseases, type 2 diabetes, steatohepatitis, and cancer. The medical anti-obe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Wan, Zhang, Jingjing, Xiao, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215703/ https://www.ncbi.nlm.nih.gov/pubmed/34163436 http://dx.doi.org/10.3389/fendo.2021.662451

Ejemplares similares

Roflumilast reduces myocardial ischemia reperfusion injury in vivo and in vitro by activating the AMPK signaling pathway
por: Liao, Bo, et al.
Publicado: (2023)

ANGPTL8 promotes adipogenic differentiation of mesenchymal stem cells: potential role in ectopic lipid deposition
por: Tang, Jian, et al.
Publicado: (2022)

17β-Estradiol Induces Mitophagy Upregulation to Protect Chondrocytes via the SIRT1-Mediated AMPK/mTOR Signaling Pathway
por: Mei, Runhong, et al.
Publicado: (2021)

AMPK Activation Mediated by Hinokitiol Inhibits Adipogenic Differentiation of Mesenchymal Stem Cells through Autophagy Flux
por: Lee, Ju-Hee, et al.
Publicado: (2018)

Roflumilast Ameliorates Isoflurane-Induced Inflammation in Astrocytes via the CREB/BDNF Signaling Pathway
por: Zhang, Chunyuan, et al.
Publicado: (2021)

Identification of small molecules as novel anti-adipogenic compounds based on Connectivity Map
por: Zhang, Shuang, et al.
Publicado: (2022)

Research progress on the role of lncRNA–miRNA networks in regulating adipogenic and osteogenic differentiation of bone marrow mesenchymal stem cells in osteoporosis
por: An, Fangyu, et al.
Publicado: (2023)

Quercetin Attenuates Osteoporosis in Orchiectomy Mice by Regulating Glucose and Lipid Metabolism via the GPRC6A/AMPK/mTOR Signaling Pathway
por: Sun, Jie, et al.
Publicado: (2022)

Toward Marrow Adipocytes: Adipogenic Trajectory of the Bone Marrow Stromal Cell Lineage
por: Matsushita, Yuki, et al.
Publicado: (2022)

Madecassoside Inhibits Body Weight Gain via Modulating SIRT1-AMPK Signaling Pathway and Activating Genes Related to Thermogenesis
por: Sun, Boju, et al.
Publicado: (2021)

Retraction of “Roflumilast Ameliorates Isoflurane-Induced Inflammation in Astrocytes via the CREB/BDNF Signaling Pathway”
por: Zhang, Chunyuan, et al.
Publicado: (2021)

Krill oil inhibited adipogenic differentiation by inducing the nuclear Nrf2 expression and the AMPK activity
por: Lee, Hyun Jeong, et al.
Publicado: (2023)

Dose-Dependent Effect of Estrogen Suppresses the Osteo-Adipogenic Transdifferentiation of Osteoblasts via Canonical Wnt Signaling Pathway
por: Gao, Bo, et al.
Publicado: (2014)

Liraglutide suppresses proliferation and induces adipogenic differentiation of 3T3-L1 cells via the Hippo-YAP signaling pathway
por: Li, Yongmei, et al.
Publicado: (2018)

Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties
por: Ribeiro Filho, Helder Veras, et al.
Publicado: (2018)

Adipogenic Gene Expression in Gilthead Sea Bream Mesenchymal Stem Cells from Different Origin
por: Salmerón, Cristina, et al.
Publicado: (2016)

The Implication of Oxidative Stress and AMPK-Nrf2 Antioxidative Signaling in Pneumonia Pathogenesis
por: Xu, Weitong, et al.
Publicado: (2020)

Canagliflozin promotes osteoblastic MC3T3-E1 differentiation via AMPK/RUNX2 and improves bone microarchitecture in type 2 diabetic mice
por: Song, Peiyang, et al.
Publicado: (2022)

FA1 Induces Pro-Inflammatory and Anti-Adipogenic Pathways/Markers in Human Myotubes Established from Lean, Obese, and Type 2 Diabetic Subjects but Not Insulin Resistance
por: Abdallah, Basem M., et al.
Publicado: (2013)

Tmod3 Phosphorylation Mediates AMPK-Dependent GLUT4 Plasma Membrane Insertion in Myoblasts
por: Shrestha, Man Mohan, et al.
Publicado: (2021)

Antidiabetic Effect of Artemether in Db/Db Mice Involves Regulation of AMPK and PI3K/Akt Pathways
por: Bai, Xiaolin, et al.
Publicado: (2020)

Roflumilast in COPD: a Brazilian perspective
por: Stirbulov, Roberto, et al.
Publicado: (2015)

Real Talk: The Inter-play Between the mTOR, AMPK, and Hexosamine Biosynthetic Pathways in Cell Signaling
por: Cork, Gentry K., et al.
Publicado: (2018)

Electroacupuncture Stimulation Regulates Adipose Lipolysis via Catecholamine Signaling Mediated by NLRP3 Suppression in Obese Rats
por: Lu, Mengjiang, et al.
Publicado: (2022)

AMPK in the Ventromedial Nucleus of the Hypothalamus: A Key Regulator for Thermogenesis
por: Liu, Hailan, et al.
Publicado: (2020)

Ndufa6 regulates adipogenic differentiation via Scd1
por: Zhang, Jingwei, et al.
Publicado: (2021)

YAP promotes osteogenesis and suppresses adipogenic differentiation by regulating β-catenin signaling
por: Pan, Jin-Xiu, et al.
Publicado: (2018)

Dual Effects of Metformin on Adipogenic Differentiation of 3T3-L1 Preadipocyte in AMPK-Dependent and Independent Manners
por: Chen, Dian, et al.
Publicado: (2018)

Buformin suppresses osteosarcoma via targeting AMPK signaling pathway
por: Ding, Yan, et al.
Publicado: (2020)

Pharmacological mechanism of roflumilast in the treatment of asthma–COPD overlap
por: Zhang, Xiaoli, et al.
Publicado: (2018)

An Optimized Pathway for the Differential Diagnosis of ACTH-Dependent Cushing’s Syndrome Based on Low-Dose Dexamethasone Suppression Test
por: Chen, Kang, et al.
Publicado: (2021)

Review of Signaling Pathways Governing MSC Osteogenic and Adipogenic Differentiation
por: James, Aaron W.
Publicado: (2013)

The Protective Effects of Melatonin Against LPS-Induced Septic Myocardial Injury: A Potential Role of AMPK-Mediated Autophagy
por: Di, Shouyin, et al.
Publicado: (2020)

Vulnerable COPD patients with comorbidities: the role of roflumilast
por: Lipari, Melissa, et al.
Publicado: (2014)

Efficacy and Safety of Roflumilast in Korean Patients with COPD
por: Lee, Jae Seung, et al.
Publicado: (2016)

Glucocorticoid Receptor α Mediates Roflumilast’s Ability to Restore Dexamethasone Sensitivity in COPD
por: Reddy, Aravind T, et al.
Publicado: (2020)

Miltefosine Suppresses Hepatic Steatosis by Activating AMPK Signal Pathway
por: Fang, Ru, et al.
Publicado: (2016)

AMPK: a master energy regulator for gonadal function
por: Bertoldo, Michael J., et al.
Publicado: (2015)

Chidamide suppresses adipogenic differentiation of bone marrow derived mesenchymal stem cells via increasing REEP2 expression
por: Zhang, Xianning, et al.
Publicado: (2023)

Estrogen receptor subtype mediated anti-inflammation and vasorelaxation via genomic and nongenomic actions in septic mice
por: Zhang, Luyun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rvho4bk67tu962acsjnd96hup4