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Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction

BACKGROUND: Drug-coated balloon (DCB) is a new technology that has emerged in recent years and has been proven to be effective and safe in the treatment of in-stent restenosis. The purpose of this article is to observe the safety and effectiveness of drug-coated balloons in patients with acute myoca...

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Autores principales: good , Little teacher is, Yellow , Damien, King , Asaka, Zhang , Jin Chun, Liu , Li Hongqiang, road , Yingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215732/
https://www.ncbi.nlm.nih.gov/pubmed/34154628
http://dx.doi.org/10.1186/s13019-021-01525-8
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author good , Little teacher is
Yellow , Damien
King , Asaka
Zhang , Jin Chun
Liu , Li Hongqiang
road , Yingmin
author_facet good , Little teacher is
Yellow , Damien
King , Asaka
Zhang , Jin Chun
Liu , Li Hongqiang
road , Yingmin
author_sort good , Little teacher is
collection PubMed
description BACKGROUND: Drug-coated balloon (DCB) is a new technology that has emerged in recent years and has been proven to be effective and safe in the treatment of in-stent restenosis. The purpose of this article is to observe the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction. METHOD: We selected 80 patients admitted to the hospital for STEMI from January 2018 to December 2019. The subjects were randomly divided into a Yinyi (Liaoning) Biotech Bingo Drug Coated Balloon treatment group (balloon group, n  = 38) and a drug-eluting stent (DES) treatment group (stent group, n  = 42). Patients were followed up to understand the incidence of major adverse cardiovascular events (MACE) at 1 month, 6 months and 1 year after surgery. Coronary angiography was rechecked 1 year after surgery to understand the late lumen loss (LLL) in the two groups. RESULT: During the one-year follow-up, the LLL of the target lesion in the balloon group was -0.12±0.46 mm, while the target lesion in the stent group was 0.14±0.37 mm ( P  <0.05). Within 1 year, the incidence of MACE in the balloon group was 11%, while the incidence of MACE in the stent group was 12%. There was no significant difference between the two groups. IN CONCLUSION: When PCI is used for STEMI, only DCB therapy is safe and effective, and has shown good clinical effects during a one-year follow-up period.
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spelling pubmed-82157322021-06-23 Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction good , Little teacher is Yellow , Damien King , Asaka Zhang , Jin Chun Liu , Li Hongqiang road , Yingmin J Cardiothorac Surg Research Article BACKGROUND: Drug-coated balloon (DCB) is a new technology that has emerged in recent years and has been proven to be effective and safe in the treatment of in-stent restenosis. The purpose of this article is to observe the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction. METHOD: We selected 80 patients admitted to the hospital for STEMI from January 2018 to December 2019. The subjects were randomly divided into a Yinyi (Liaoning) Biotech Bingo Drug Coated Balloon treatment group (balloon group, n  = 38) and a drug-eluting stent (DES) treatment group (stent group, n  = 42). Patients were followed up to understand the incidence of major adverse cardiovascular events (MACE) at 1 month, 6 months and 1 year after surgery. Coronary angiography was rechecked 1 year after surgery to understand the late lumen loss (LLL) in the two groups. RESULT: During the one-year follow-up, the LLL of the target lesion in the balloon group was -0.12±0.46 mm, while the target lesion in the stent group was 0.14±0.37 mm ( P  <0.05). Within 1 year, the incidence of MACE in the balloon group was 11%, while the incidence of MACE in the stent group was 12%. There was no significant difference between the two groups. IN CONCLUSION: When PCI is used for STEMI, only DCB therapy is safe and effective, and has shown good clinical effects during a one-year follow-up period. BioMed Central 2021-06-21 /pmc/articles/PMC8215732/ /pubmed/34154628 http://dx.doi.org/10.1186/s13019-021-01525-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
good , Little teacher is
Yellow , Damien
King , Asaka
Zhang , Jin Chun
Liu , Li Hongqiang
road , Yingmin
Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction
title Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction
title_full Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction
title_fullStr Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction
title_full_unstemmed Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction
title_short Study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction
title_sort study on the safety and effectiveness of drug-coated balloons in patients with acute myocardial infarction
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215732/
https://www.ncbi.nlm.nih.gov/pubmed/34154628
http://dx.doi.org/10.1186/s13019-021-01525-8
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