Integrated multi-omics analyses on patient-derived CRC organoids highlight altered molecular pathways in colorectal cancer progression involving PTEN

BACKGROUND: Colorectal cancer (CRC) represents the fourth leading cause of cancer-related deaths. The heterogeneity of CRC identity limits the usage of cell lines to study this type of tumor because of the limited representation of multiple features of the original malignancy. Patient-derived colon...

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Detalles Bibliográficos
Autores principales: Codrich, Marta, Dalla, Emiliano, Mio, Catia, Antoniali, Giulia, Malfatti, Matilde Clarissa, Marzinotto, Stefania, Pierobon, Mariaelena, Baldelli, Elisa, Di Loreto, Carla, Damante, Giuseppe, Terrosu, Giovanni, Pucillo, Carlo Ennio Michele, Tell, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215814/
https://www.ncbi.nlm.nih.gov/pubmed/34154611
http://dx.doi.org/10.1186/s13046-021-01986-8

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