Cargando…

Targeting WD repeat domain 5 enhances chemosensitivity and inhibits proliferation and programmed death-ligand 1 expression in bladder cancer

BACKGROUND: Chemotherapy and/or immunotherapy are first-line treatments for advanced muscle-invasive bladder cancer (BCa), but the unsatisfactory objective response rate to these treatments yields poor 5-year patient survival. Discovery of therapeutic targets essential for BCa maintenance is critica...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Jingtong, Zhou, Qianghua, Xie, Keji, Cheng, Liang, Peng, Shengmeng, Xie, Ruihui, Liu, Lixuan, Zhang, Yangjie, Dong, Wen, Han, Jinli, Huang, Ming, Chen, Yuelong, Lin, Tianxin, Huang, Jian, Chen, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215817/ https://www.ncbi.nlm.nih.gov/pubmed/34154613 http://dx.doi.org/10.1186/s13046-021-01989-5

Ejemplares similares

WD repeat domain 5 promotes chemoresistance and Programmed Death-Ligand 1 expression in prostate cancer
por: Zhou, Qianghua, et al.
Publicado: (2021)

HSF1 facilitates the multistep process of lymphatic metastasis in bladder cancer via a novel PRMT5‐WDR5‐dependent transcriptional program
por: Huang, Ming, et al.
Publicado: (2022)

TSPAN18 facilitates bone metastasis of prostate cancer by protecting STIM1 from TRIM32-mediated ubiquitination
por: Zhou, Qianghua, et al.
Publicado: (2023)

Heterogeneous nuclear ribonucleoprotein K is associated with poor prognosis and regulates proliferation and apoptosis in bladder cancer
por: Chen, Xu, et al.
Publicado: (2016)

Circular RNA ACVR2A suppresses bladder cancer cells proliferation and metastasis through miR-626/EYA4 axis
por: Dong, Wei, et al.
Publicado: (2019)

WD repeat domain 48 promotes hepatocellular carcinoma progression by stabilizing c‐Myc
por: Li, Bo, et al.
Publicado: (2022)

ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer
por: Zhang, Qiang, et al.
Publicado: (2023)

Suppression of Ribosome Biogenesis by Targeting WD Repeat Domain 12 (WDR12) Inhibits Glioma Stem-Like Cell Growth
por: Mi, Lanjuan, et al.
Publicado: (2021)

A novel WD40-repeat protein involved in formation of epidermal bladder cells in the halophyte quinoa
por: Imamura, Tomohiro, et al.
Publicado: (2020)

WDSPdb: a database for WD40-repeat proteins
por: Wang, Yang, et al.
Publicado: (2014)

Editorial: Signaling through WD-Repeat Proteins in Plants
por: Villanueva, Marco A., et al.
Publicado: (2016)

ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer (Adv. Sci. 11/2023)
por: Zhang, Qiang, et al.
Publicado: (2023)

A novel AR translational regulator lncRNA LBCS inhibits castration resistance of prostate cancer
por: Gu, Peng, et al.
Publicado: (2019)

Function and regulation of F-box/WD repeat-containing protein 7
por: Zhang, Zheng, et al.
Publicado: (2020)

Prognostic role of ring finger and WD repeat domain 3 and immune cell infiltration in hepatocellular carcinoma
por: Miao, Yan-Dong, et al.
Publicado: (2023)

Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
por: Jin, Wenxing, et al.
Publicado: (2016)

A Pan-Cancer Analysis of the Oncogenic Role of WD Repeat Domain 74 in Multiple Tumors
por: Wu, Xiaoxuan, et al.
Publicado: (2022)

The LuWD40-1 Gene Encoding WD Repeat Protein Regulates Growth and Pollen Viability in Flax (Linum Usitatissimum L.)
por: Kumar, Santosh, et al.
Publicado: (2013)

F-box and WD repeat domain containing 7 inhibits the activation of hepatic stellate cells by degrading delta-like ligand 1 to block Notch signaling pathway
por: Sun, Yufeng, et al.
Publicado: (2023)

The WD-repeat protein superfamily in Arabidopsis: conservation and divergence in structure and function
por: van Nocker, Steven, et al.
Publicado: (2003)

A Method for WD40 Repeat Detection and Secondary Structure Prediction
por: Wang, Yang, et al.
Publicado: (2013)

WD40-Repeat Proteins in Ciliopathies and Congenital Disorders of Endocrine System
por: Kim, Yeonjoo, et al.
Publicado: (2020)

Overexpression of F-box and WD repeat domain containing 7 prevents tumor growth of bladder cancer cells through regulating SREBP1a
por: Liu, Fang, et al.
Publicado: (2022)

UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer
por: Peng, Shengmeng, et al.
Publicado: (2022)

Aberrant methylation of WD‐repeat protein 41 contributes to tumour progression in triple‐negative breast cancer
por: Wang, Han, et al.
Publicado: (2020)

WD Repeat Domain 1 Deficiency Inhibits Neointima Formation in Mice Carotid Artery by Modulation of Smooth Muscle Cell Migration and Proliferation
por: Hu, JiSheng, et al.
Publicado: (2020)

Autophagy-Related Gene WD Repeat Domain 45B Promotes Tumor Proliferation and Migration of Hepatocellular Carcinoma through the Akt/mTOR Signaling Pathway
por: Li, Jiahao, et al.
Publicado: (2023)

A WD40 Repeat Protein from Camellia sinensis Regulates Anthocyanin and Proanthocyanidin Accumulation through the Formation of MYB–bHLH–WD40 Ternary Complexes
por: Liu, Yajun, et al.
Publicado: (2018)

Recent Progress in Modulation of WD40-Repeat Domain 5 Protein (WDR5): Inhibitors and Degraders
por: Gurung, Raju, et al.
Publicado: (2023)

PTEN downregulates WD repeat-containing protein 66 in salivary adenoid cystic carcinoma
por: Cao, Yu, et al.
Publicado: (2019)

Nemitin, a Novel Map8/Map1s Interacting Protein with Wd40 Repeats
por: Wang, Wei, et al.
Publicado: (2012)

Association studies of WD repeat domain 3 and chitobiosyldiphosphodolichol beta-mannosyltransferase genes with schizophrenia in a Japanese population
por: Kobayashi, Momoko, et al.
Publicado: (2018)

F-Box/WD Repeat Domain-Containing 7 Induces Chemotherapy Resistance in Colorectal Cancer Stem Cells
por: Honma, Shusaku, et al.
Publicado: (2019)

Expression of WD Repeat Domain 5 (WDR5) is Associated with Progression and Reduced Prognosis in Papillary Thyroid Carcinoma
por: Xu, Wenchao, et al.
Publicado: (2019)

WD repeat domain 5 promotes the development of late-onset preeclampsia by activating nuclear factor kappa B
por: Zhao, Xudong, et al.
Publicado: (2023)

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer
por: Xiao, Kanghua, et al.
Publicado: (2023)

Crystal structure of the WD40 domain dimer of LRRK2
por: Zhang, Pengfei, et al.
Publicado: (2019)

Genome-wide analysis of WD40 protein family and functional characterization of BvWD40-82 in sugar beet
por: Wu, Zhirui, et al.
Publicado: (2023)

YAO is a nucleolar WD40-repeat protein critical for embryogenesis and gametogenesis in Arabidopsis
por: Li, Hong-Ju, et al.
Publicado: (2010)

Identification of WD-Repeat Protein 72 as a Novel Prognostic Biomarker in Non-Small-Cell Lung Cancer
por: Shi, Guanglin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2tejbkm06jbdqs047hsj13bqq6