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The promising shadow of microbubble over medical sciences: from fighting wide scope of prevalence disease to cancer eradication
Microbubbles are typically 0.5–10 μm in size. Their size tends to make it easier for medication delivery mechanisms to navigate the body by allowing them to be swallowed more easily. The gas included in the microbubble is surrounded by a membrane that may consist of biocompatible biopolymers, polyme...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215828/ https://www.ncbi.nlm.nih.gov/pubmed/34154581 http://dx.doi.org/10.1186/s12929-021-00744-4 |
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author | Jangjou, Ali Meisami, Amir Hossein Jamali, Kazem Niakan, Mohammad Hadi Abbasi, Milad Shafiee, Mostafa Salehi, Majid Hosseinzadeh, Ahmad Amani, Ali Mohammad Vaez, Ahmad |
author_facet | Jangjou, Ali Meisami, Amir Hossein Jamali, Kazem Niakan, Mohammad Hadi Abbasi, Milad Shafiee, Mostafa Salehi, Majid Hosseinzadeh, Ahmad Amani, Ali Mohammad Vaez, Ahmad |
author_sort | Jangjou, Ali |
collection | PubMed |
description | Microbubbles are typically 0.5–10 μm in size. Their size tends to make it easier for medication delivery mechanisms to navigate the body by allowing them to be swallowed more easily. The gas included in the microbubble is surrounded by a membrane that may consist of biocompatible biopolymers, polymers, surfactants, proteins, lipids, or a combination thereof. One of the most effective implementation techniques for tiny bubbles is to apply them as a drug carrier that has the potential to activate ultrasound (US); this allows the drug to be released by US. Microbubbles are often designed to preserve and secure medicines or substances before they have reached a certain area of concern and, finally, US is used to disintegrate microbubbles, triggering site-specific leakage/release of biologically active drugs. They have excellent therapeutic potential in a wide range of common diseases. In this article, we discussed microbubbles and their advantageous medicinal uses in the treatment of certain prevalent disorders, including Parkinson's disease, Alzheimer's disease, cardiovascular disease, diabetic condition, renal defects, and finally, their use in the treatment of various forms of cancer as well as their incorporation with nanoparticles. Using microbubble technology as a novel carrier, the ability to prevent and eradicate prevalent diseases has strengthened the promise of effective care to improve patient well-being and life expectancy. |
format | Online Article Text |
id | pubmed-8215828 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-82158282021-06-23 The promising shadow of microbubble over medical sciences: from fighting wide scope of prevalence disease to cancer eradication Jangjou, Ali Meisami, Amir Hossein Jamali, Kazem Niakan, Mohammad Hadi Abbasi, Milad Shafiee, Mostafa Salehi, Majid Hosseinzadeh, Ahmad Amani, Ali Mohammad Vaez, Ahmad J Biomed Sci Review Microbubbles are typically 0.5–10 μm in size. Their size tends to make it easier for medication delivery mechanisms to navigate the body by allowing them to be swallowed more easily. The gas included in the microbubble is surrounded by a membrane that may consist of biocompatible biopolymers, polymers, surfactants, proteins, lipids, or a combination thereof. One of the most effective implementation techniques for tiny bubbles is to apply them as a drug carrier that has the potential to activate ultrasound (US); this allows the drug to be released by US. Microbubbles are often designed to preserve and secure medicines or substances before they have reached a certain area of concern and, finally, US is used to disintegrate microbubbles, triggering site-specific leakage/release of biologically active drugs. They have excellent therapeutic potential in a wide range of common diseases. In this article, we discussed microbubbles and their advantageous medicinal uses in the treatment of certain prevalent disorders, including Parkinson's disease, Alzheimer's disease, cardiovascular disease, diabetic condition, renal defects, and finally, their use in the treatment of various forms of cancer as well as their incorporation with nanoparticles. Using microbubble technology as a novel carrier, the ability to prevent and eradicate prevalent diseases has strengthened the promise of effective care to improve patient well-being and life expectancy. BioMed Central 2021-06-21 /pmc/articles/PMC8215828/ /pubmed/34154581 http://dx.doi.org/10.1186/s12929-021-00744-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Review Jangjou, Ali Meisami, Amir Hossein Jamali, Kazem Niakan, Mohammad Hadi Abbasi, Milad Shafiee, Mostafa Salehi, Majid Hosseinzadeh, Ahmad Amani, Ali Mohammad Vaez, Ahmad The promising shadow of microbubble over medical sciences: from fighting wide scope of prevalence disease to cancer eradication |
title | The promising shadow of microbubble over medical sciences: from fighting wide scope of prevalence disease to cancer eradication |
title_full | The promising shadow of microbubble over medical sciences: from fighting wide scope of prevalence disease to cancer eradication |
title_fullStr | The promising shadow of microbubble over medical sciences: from fighting wide scope of prevalence disease to cancer eradication |
title_full_unstemmed | The promising shadow of microbubble over medical sciences: from fighting wide scope of prevalence disease to cancer eradication |
title_short | The promising shadow of microbubble over medical sciences: from fighting wide scope of prevalence disease to cancer eradication |
title_sort | promising shadow of microbubble over medical sciences: from fighting wide scope of prevalence disease to cancer eradication |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215828/ https://www.ncbi.nlm.nih.gov/pubmed/34154581 http://dx.doi.org/10.1186/s12929-021-00744-4 |
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