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The nuclear periphery is a scaffold for tissue-specific enhancers
Nuclear architecture influences gene regulation and cell identity by controlling the three-dimensional organization of genes and their distal regulatory sequences, which may be far apart in linear space. The genome is functionally and spatially segregated in the eukaryotic nucleus with transcription...
Autores principales: | Smith, Cheryl L, Poleshko, Andrey, Epstein, Jonathan A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216274/ https://www.ncbi.nlm.nih.gov/pubmed/34023908 http://dx.doi.org/10.1093/nar/gkab392 |
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