An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands

U1 small nuclear ribonucleoparticle (U1 snRNP) plays a central role during RNA processing. Previous structures of U1 snRNP revealed how the ribonucleoparticle is organized and recognizes the pre-mRNA substrate at the exon–intron junction. As with many other ribonucleoparticles involved in RNA metabo...

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Detalles Bibliográficos
Autores principales: Campagne, Sébastien, de Vries, Tebbe, Malard, Florian, Afanasyev, Pavel, Dorn, Georg, Dedic, Emil, Kohlbrecher, Joachim, Boehringer, Daniel, Cléry, Antoine, Allain, Frédéric H-T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216277/
https://www.ncbi.nlm.nih.gov/pubmed/33677607
http://dx.doi.org/10.1093/nar/gkab135

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