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Cooperative DNA looping by PRC2 complexes

Polycomb repressive complex 2 (PRC2) is an essential protein complex that silences gene expression via post-translational modifications of chromatin. This paper combined homology modeling, atomistic and coarse-grained molecular dynamics simulations, and single-molecule force spectroscopy experiments...

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Detalles Bibliográficos
Autores principales:	Lin, Xingcheng, Leicher, Rachel, Liu, Shixin, Zhang, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216278/ https://www.ncbi.nlm.nih.gov/pubmed/34057467 http://dx.doi.org/10.1093/nar/gkab441

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