A Case of IgG4-Related Kidney Disease Developing While on Steroid Treatment for Autoimmune IgG4 Pancreatitis

IgG4 (immunoglobulin G4)-related systemic disease is an autoimmune process affecting multiple organ systems. This inflammatory process can present as but not limited to pancreatitis, cholangitis, or unspecified kidney disease. In this case, our patient developed IgG4-related kidney disease while alr...

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Detalles Bibliográficos
Autores principales: Reyes, Jonathan Vincent M., Maldonado, Dawn, Stern, Aaron S., Brown, Maritza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216373/
https://www.ncbi.nlm.nih.gov/pubmed/34151624
http://dx.doi.org/10.1177/23247096211026500
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author Reyes, Jonathan Vincent M.
Maldonado, Dawn
Stern, Aaron S.
Brown, Maritza
author_facet Reyes, Jonathan Vincent M.
Maldonado, Dawn
Stern, Aaron S.
Brown, Maritza
author_sort Reyes, Jonathan Vincent M.
collection PubMed
description IgG4 (immunoglobulin G4)-related systemic disease is an autoimmune process affecting multiple organ systems. This inflammatory process can present as but not limited to pancreatitis, cholangitis, or unspecified kidney disease. In this case, our patient developed IgG4-related kidney disease while already on a prolonged steroid course for IgG4-related pancreatitis. The patient ultimately had renal recovery after starting a higher dose of prednisone, but also developed steroid-related complications. This case further highlights the relationship between IgG4 diseases now termed IgG4-related systemic disease. This case brings to light the need for further investigative research into ideal steroid dosing, as well as steroid-sparing agents for IgG4-related systemic disease.
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spelling pubmed-82163732021-06-30 A Case of IgG4-Related Kidney Disease Developing While on Steroid Treatment for Autoimmune IgG4 Pancreatitis Reyes, Jonathan Vincent M. Maldonado, Dawn Stern, Aaron S. Brown, Maritza J Investig Med High Impact Case Rep Case Report IgG4 (immunoglobulin G4)-related systemic disease is an autoimmune process affecting multiple organ systems. This inflammatory process can present as but not limited to pancreatitis, cholangitis, or unspecified kidney disease. In this case, our patient developed IgG4-related kidney disease while already on a prolonged steroid course for IgG4-related pancreatitis. The patient ultimately had renal recovery after starting a higher dose of prednisone, but also developed steroid-related complications. This case further highlights the relationship between IgG4 diseases now termed IgG4-related systemic disease. This case brings to light the need for further investigative research into ideal steroid dosing, as well as steroid-sparing agents for IgG4-related systemic disease. SAGE Publications 2021-06-19 /pmc/articles/PMC8216373/ /pubmed/34151624 http://dx.doi.org/10.1177/23247096211026500 Text en © 2021 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Reyes, Jonathan Vincent M.
Maldonado, Dawn
Stern, Aaron S.
Brown, Maritza
A Case of IgG4-Related Kidney Disease Developing While on Steroid Treatment for Autoimmune IgG4 Pancreatitis
title A Case of IgG4-Related Kidney Disease Developing While on Steroid Treatment for Autoimmune IgG4 Pancreatitis
title_full A Case of IgG4-Related Kidney Disease Developing While on Steroid Treatment for Autoimmune IgG4 Pancreatitis
title_fullStr A Case of IgG4-Related Kidney Disease Developing While on Steroid Treatment for Autoimmune IgG4 Pancreatitis
title_full_unstemmed A Case of IgG4-Related Kidney Disease Developing While on Steroid Treatment for Autoimmune IgG4 Pancreatitis
title_short A Case of IgG4-Related Kidney Disease Developing While on Steroid Treatment for Autoimmune IgG4 Pancreatitis
title_sort case of igg4-related kidney disease developing while on steroid treatment for autoimmune igg4 pancreatitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216373/
https://www.ncbi.nlm.nih.gov/pubmed/34151624
http://dx.doi.org/10.1177/23247096211026500
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