Prenatal Lead (Pb) Exposure and Peripheral Blood DNA Methylation (5mC) and Hydroxymethylation (5hmC) in Mexican Adolescents from the ELEMENT Birth Cohort

BACKGROUND: Gestational lead (Pb) exposure can adversely affect offspring health through multiple mechanisms, including epigenomic alterations via DNA methylation (5mC) and hydroxymethylation (5hmC), an intermediate in oxidative demethylation. Most current methods do not distinguish between 5mC and...

Descripción completa

Detalles Bibliográficos
Autores principales: Rygiel, Christine A., Goodrich, Jaclyn M., Solano-González, Maritsa, Mercado-García, Adriana, Hu, Howard, Téllez-Rojo, Martha M., Peterson, Karen E., Dolinoy, Dana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216410/
https://www.ncbi.nlm.nih.gov/pubmed/34152198
http://dx.doi.org/10.1289/EHP8507

Ejemplares similares

Ejemplares similares