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In vivo antitumor effects of carboxymethyl chitosan-conjugated triptolide after oral administration

The purpose of this study is to evaluate in vitro and in vivo antitumor efficacy and subacute toxicity of triptolide (TP) prodrug, a conjugate between TP and carboxymethyl chitosan (CC). The CCTP conjugate contained 4∼ wt % TP and displayed excellent aqueous solubility (5 mg/mL) as compared to the n...

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Detalles Bibliográficos
Autores principales:	Zeng, Huahui, Zhu, Xin, Tian, Qikang, Yan, Yinyin, Zhang, Lan, Yan, Min, Li, Ruiqin, Li, Xiaofang, Wang, Guoqiang, Ma, Jinlian, Su, Yufang, Zhang, Xiangbo, Ma, Linyu, Zhang, Zhenqiang, Wu, Xiangxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216443/ https://www.ncbi.nlm.nih.gov/pubmed/32508161 http://dx.doi.org/10.1080/10717544.2020.1770370

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