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Repaglinide-loaded nanostructured lipid carriers with different particle sizes for improving oral absorption: preparation, characterization, pharmacokinetics, and in situ intestinal perfusion

Repaglinide-loaded nanostructured lipid carriers (REP-NLCs) with different particle sizes were successfully designed and prepared to investigate the permeation and absorption ability by in situ single-pass intestinal perfusion (SPIP) study and pharmacokinetics. Both of the formulations prepared by s...

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Detalles Bibliográficos
Autores principales: Wu, Lei, Zhao, Lin, Su, Xitong, Zhang, Peng, Ling, Guixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216444/
https://www.ncbi.nlm.nih.gov/pubmed/31729898
http://dx.doi.org/10.1080/10717544.2019.1689313

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