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Enhanced anti-hepatoma effect of a novel curcumin analog C086 via solid dispersion technology

The novel curcumin analog C086, previously identified as an oral novel heat shock protein 90 (Hsp90) inhibitor, was found to exhibit anti-hepatoma activity in vitro and in vivo. However, owing to its limited aqueous solubility, the usage of C086 in the clinical application was restricted. This resea...

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Detalles Bibliográficos
Autores principales: Deng, Yanping, Chen, Chun, Xiao, Zhifeng, Huang, Xiuwang, Xu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216446/
https://www.ncbi.nlm.nih.gov/pubmed/32597247
http://dx.doi.org/10.1080/10717544.2020.1785051