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Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex

The CCR4 and CAF1 deadenylases physically interact to form the CCR4-CAF1 complex and function as the catalytic core of the larger CCR4-NOT complex. Together, they are responsible for the eventual removal of the 3′-poly(A) tail from essentially all cellular mRNAs and consequently play a central role...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Khazina, Elena, Izaurralde, Elisa, Weichenrieder, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216464/
https://www.ncbi.nlm.nih.gov/pubmed/34038562
http://dx.doi.org/10.1093/nar/gkab414

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