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Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex
The CCR4 and CAF1 deadenylases physically interact to form the CCR4-CAF1 complex and function as the catalytic core of the larger CCR4-NOT complex. Together, they are responsible for the eventual removal of the 3′-poly(A) tail from essentially all cellular mRNAs and consequently play a central role...
Autores principales: | Chen, Ying, Khazina, Elena, Izaurralde, Elisa, Weichenrieder, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216464/ https://www.ncbi.nlm.nih.gov/pubmed/34038562 http://dx.doi.org/10.1093/nar/gkab414 |
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