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The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination
Post-transcriptional modification of tRNA wobble adenosine into inosine is crucial for decoding multiple mRNA codons by a single tRNA. The eukaryotic wobble adenosine-to-inosine modification is catalysed by the ADAT (ADAT2/ADAT3) complex that modifies up to eight tRNAs, requiring a full tRNA for act...
Autores principales: | Ramos-Morales, Elizabeth, Bayam, Efil, Del-Pozo-Rodríguez, Jordi, Salinas-Giegé, Thalia, Marek, Martin, Tilly, Peggy, Wolff, Philippe, Troesch, Edouard, Ennifar, Eric, Drouard, Laurence, Godin, Juliette D, Romier, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216470/ https://www.ncbi.nlm.nih.gov/pubmed/34057470 http://dx.doi.org/10.1093/nar/gkab436 |
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