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What makes a type IIA topoisomerase a gyrase or a Topo IV?

Type IIA topoisomerases catalyze a variety of different reactions: eukaryotic topoisomerase II relaxes DNA in an ATP-dependent reaction, whereas the bacterial representatives gyrase and topoisomerase IV (Topo IV) preferentially introduce negative supercoils into DNA (gyrase) or decatenate DNA (Topo ...

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Detalles Bibliográficos
Autores principales:	Hirsch, Jana, Klostermeier, Dagmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Survey and Summary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216471/ https://www.ncbi.nlm.nih.gov/pubmed/33905522 http://dx.doi.org/10.1093/nar/gkab270

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