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Systemic CLIP-seq analysis and game theory approach to model microRNA mode of binding

microRNAs (miRNAs) associate with Ago proteins to post-transcriptionally silence gene expression by targeting mRNAs. To characterize the modes of miRNA-binding, we developed a novel computational framework, called optiCLIP, which considers the reproducibility of the identified peaks among replicates...

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Detalles Bibliográficos
Autores principales:	Serra, Fabrizio, Bottini, Silvia, Pratella, David, Stathopoulou, Maria G, Sebille, Wanda, El-Hami, Loubna, Repetto, Emanuela, Mauduit, Claire, Benahmed, Mohamed, Grandjean, Valerie, Trabucchi, Michele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216473/ https://www.ncbi.nlm.nih.gov/pubmed/33823551 http://dx.doi.org/10.1093/nar/gkab198

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