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Acylation of the antimicrobial peptide CAMEL for cancer gene therapy

Obtaining ideal gene delivery vectors is still a major goal in cancer gene therapy. CAMEL, a short hybrid antimicrobial peptide, can kill cancer cells by membrane lysis. In this study, we constructed a series of non-viral vectors by attaching fatty acids with different chain lengths to the N-terminu...

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Detalles Bibliográficos
Autores principales: Song, Jingjing, Ma, Panpan, Huang, Sujie, Wang, Juanli, Xie, Huan, Jia, Bo, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216477/
https://www.ncbi.nlm.nih.gov/pubmed/32611259
http://dx.doi.org/10.1080/10717544.2020.1787556

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