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An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2

In this retrospective study, a cohort of 67 subjects vaccinated with AZD1222 was retrospectively observed. Consistently with published findings, no serious adverse event was reported, and all adverse events reported (fever, muscle ache and/or pain in the site of injection) had resolved by day 8. Of...

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Autores principales: Cerino, Pellegrino, Coppola, Annachiara, Pierri, Biancamaria, Volzone, Palmiero, Bruzzese, Dario, Pierri, Andrea, Ferro, Amedeo, Schiavi, Daniela, Coppola, Antonio, Miniero, Stefano, Atripaldi, Luigi, Pirozzi, Caterina, Rusciano, Pasquale, Macri, Alessandra, Boenzi, Rita, Sale, Silvia, Brambilla, Gianfranco, Buonerba, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216649/
https://www.ncbi.nlm.nih.gov/pubmed/34290884
http://dx.doi.org/10.2144/fsoa-2021-0064
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author Cerino, Pellegrino
Coppola, Annachiara
Pierri, Biancamaria
Volzone, Palmiero
Bruzzese, Dario
Pierri, Andrea
Ferro, Amedeo
Schiavi, Daniela
Coppola, Antonio
Miniero, Stefano
Atripaldi, Luigi
Pirozzi, Caterina
Rusciano, Pasquale
Macri, Alessandra
Boenzi, Rita
Sale, Silvia
Brambilla, Gianfranco
Buonerba, Carlo
author_facet Cerino, Pellegrino
Coppola, Annachiara
Pierri, Biancamaria
Volzone, Palmiero
Bruzzese, Dario
Pierri, Andrea
Ferro, Amedeo
Schiavi, Daniela
Coppola, Antonio
Miniero, Stefano
Atripaldi, Luigi
Pirozzi, Caterina
Rusciano, Pasquale
Macri, Alessandra
Boenzi, Rita
Sale, Silvia
Brambilla, Gianfranco
Buonerba, Carlo
author_sort Cerino, Pellegrino
collection PubMed
description In this retrospective study, a cohort of 67 subjects vaccinated with AZD1222 was retrospectively observed. Consistently with published findings, no serious adverse event was reported, and all adverse events reported (fever, muscle ache and/or pain in the site of injection) had resolved by day 8. Of note, some citizens were prescribed low-dose aspirin and even heparin for thrombosis prevention. We also found variations in laboratory test results (full blood count and chemistry) on day 1 compared with day 8. Physicians should be aware that no prevention therapy for thrombosis is currently recommended, given the very low incidence of this side effect. Additional studies are warranted to interpret our findings.
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spelling pubmed-82166492021-06-21 An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2 Cerino, Pellegrino Coppola, Annachiara Pierri, Biancamaria Volzone, Palmiero Bruzzese, Dario Pierri, Andrea Ferro, Amedeo Schiavi, Daniela Coppola, Antonio Miniero, Stefano Atripaldi, Luigi Pirozzi, Caterina Rusciano, Pasquale Macri, Alessandra Boenzi, Rita Sale, Silvia Brambilla, Gianfranco Buonerba, Carlo Future Sci OA Short Communication In this retrospective study, a cohort of 67 subjects vaccinated with AZD1222 was retrospectively observed. Consistently with published findings, no serious adverse event was reported, and all adverse events reported (fever, muscle ache and/or pain in the site of injection) had resolved by day 8. Of note, some citizens were prescribed low-dose aspirin and even heparin for thrombosis prevention. We also found variations in laboratory test results (full blood count and chemistry) on day 1 compared with day 8. Physicians should be aware that no prevention therapy for thrombosis is currently recommended, given the very low incidence of this side effect. Additional studies are warranted to interpret our findings. Future Science Ltd 2021-06-15 /pmc/articles/PMC8216649/ /pubmed/34290884 http://dx.doi.org/10.2144/fsoa-2021-0064 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Short Communication
Cerino, Pellegrino
Coppola, Annachiara
Pierri, Biancamaria
Volzone, Palmiero
Bruzzese, Dario
Pierri, Andrea
Ferro, Amedeo
Schiavi, Daniela
Coppola, Antonio
Miniero, Stefano
Atripaldi, Luigi
Pirozzi, Caterina
Rusciano, Pasquale
Macri, Alessandra
Boenzi, Rita
Sale, Silvia
Brambilla, Gianfranco
Buonerba, Carlo
An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2
title An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2
title_full An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2
title_fullStr An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2
title_full_unstemmed An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2
title_short An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2
title_sort observational study of a cohort of citizens receiving the azd1222 vaccine against sars-cov-2
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216649/
https://www.ncbi.nlm.nih.gov/pubmed/34290884
http://dx.doi.org/10.2144/fsoa-2021-0064
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