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Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice

BACKGROUND: Meg3 has been shown to attenuate T2DM bone autophagy by activating p62 to inhibit bone formation. However, whether exercise can reverse this process to promote T2DM bone formation and its mechanism remains unknown. METHODS: A T2DM mouse model was established by a high-fat diet and STZ in...

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Detalles Bibliográficos
Autores principales:	Chen, Xianghe, Yang, Kang, Jin, Xing, Meng, Zhaoxiang, Liu, Bo, Yu, Huilin, Lu, Pengcheng, Wang, Kui, Fan, Zhangling, Tang, Ziang, Zhang, Feng, Liu, Chengye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216663/ https://www.ncbi.nlm.nih.gov/pubmed/34168475 http://dx.doi.org/10.2147/DMSO.S299744

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