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Klotho Inhibits Proliferation in a RET Fusion Model of Papillary Thyroid Cancer by Regulating the Wnt/β-Catenin Pathway

PURPOSE: We aimed to investigate the mechanisms of action on Klotho that underlie cancer development in RET fusion models of human papillary thyroid cancer (PTC). MATERIALS AND METHODS: Normal Nthy-ori 3-1 thyroid cells and two PTC cell lines (BHP10-3 and TPC-1), which were used as RET fusion models...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Jiang, Liang, Wu, Jiang, Dong, HaiFang, Zhao, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216664/
https://www.ncbi.nlm.nih.gov/pubmed/34168498
http://dx.doi.org/10.2147/CMAR.S295086