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Antimicrobial treatment of Corynebacterium striatum invasive infections: a systematic review
The aim of this study was to establish an evidence-based guideline for the antibiotic treatment of Corynebacterium striatum infections. Several electronic databases were systematically searched for clinical trials, observational studies or individual cases on patients of any age and gender with syst...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto de Medicina Tropical de São Paulo
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216692/ https://www.ncbi.nlm.nih.gov/pubmed/34161555 http://dx.doi.org/10.1590/S1678-9946202163049 |
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author | Milosavljevic, Milos N. Milosavljevic, Jovana Z. Kocovic, Aleksandar G. Stefanovic, Srdjan M. Jankovic, Slobodan M. Djesevic, Miralem Milentijevic, Milica N. |
author_facet | Milosavljevic, Milos N. Milosavljevic, Jovana Z. Kocovic, Aleksandar G. Stefanovic, Srdjan M. Jankovic, Slobodan M. Djesevic, Miralem Milentijevic, Milica N. |
author_sort | Milosavljevic, Milos N. |
collection | PubMed |
description | The aim of this study was to establish an evidence-based guideline for the antibiotic treatment of Corynebacterium striatum infections. Several electronic databases were systematically searched for clinical trials, observational studies or individual cases on patients of any age and gender with systemic inflammatory response syndrome, harboring C. striatum isolated from body fluids or tissues in which it is not normally present. C. striatum had to be identified as the only causative agent of the invasive infection, and its isolation from blood, body fluids or tissues had to be confirmed by one of the more advanced diagnostic methods (biochemical methods, mass spectrometry and/or gene sequencing). This systematic review included 42 studies that analyzed 85 individual cases with various invasive infections caused by C. striatum. More than one isolate of C. striatum exhibited 100% susceptibility to vancomycin, linezolid, teicoplanin, piperacillin-tazobactam, amoxicillin-clavulanate and cefuroxime. On the other hand, some strains of this bacterium showed a high degree of resistance to fluoroquinolones, to the majority majority of β-lactams, aminoglycosides, macrolides, lincosamides and cotrimoxazole. Despite the antibiotic treatment, fatal outcomes were reported in almost 20% of the patients included in this study. Gene sequencing methods should be the gold standard for the identification of C. striatum, while MALDI-TOF and the Vitek system can be used as alternative methods. Vancomycin should be used as the antibiotic of choice for the treatment of C. striatum infections, in monotherapy or in combination with piperacillin-tazobactam. Alternatively, linezolid, teicoplanin or daptomycin may be used in severe infections, while amoxicillin-clavulanate may be used to treat mild infections caused by C. striatum. |
format | Online Article Text |
id | pubmed-8216692 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Instituto de Medicina Tropical de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-82166922021-06-30 Antimicrobial treatment of Corynebacterium striatum invasive infections: a systematic review Milosavljevic, Milos N. Milosavljevic, Jovana Z. Kocovic, Aleksandar G. Stefanovic, Srdjan M. Jankovic, Slobodan M. Djesevic, Miralem Milentijevic, Milica N. Rev Inst Med Trop Sao Paulo Review The aim of this study was to establish an evidence-based guideline for the antibiotic treatment of Corynebacterium striatum infections. Several electronic databases were systematically searched for clinical trials, observational studies or individual cases on patients of any age and gender with systemic inflammatory response syndrome, harboring C. striatum isolated from body fluids or tissues in which it is not normally present. C. striatum had to be identified as the only causative agent of the invasive infection, and its isolation from blood, body fluids or tissues had to be confirmed by one of the more advanced diagnostic methods (biochemical methods, mass spectrometry and/or gene sequencing). This systematic review included 42 studies that analyzed 85 individual cases with various invasive infections caused by C. striatum. More than one isolate of C. striatum exhibited 100% susceptibility to vancomycin, linezolid, teicoplanin, piperacillin-tazobactam, amoxicillin-clavulanate and cefuroxime. On the other hand, some strains of this bacterium showed a high degree of resistance to fluoroquinolones, to the majority majority of β-lactams, aminoglycosides, macrolides, lincosamides and cotrimoxazole. Despite the antibiotic treatment, fatal outcomes were reported in almost 20% of the patients included in this study. Gene sequencing methods should be the gold standard for the identification of C. striatum, while MALDI-TOF and the Vitek system can be used as alternative methods. Vancomycin should be used as the antibiotic of choice for the treatment of C. striatum infections, in monotherapy or in combination with piperacillin-tazobactam. Alternatively, linezolid, teicoplanin or daptomycin may be used in severe infections, while amoxicillin-clavulanate may be used to treat mild infections caused by C. striatum. Instituto de Medicina Tropical de São Paulo 2021-06-18 /pmc/articles/PMC8216692/ /pubmed/34161555 http://dx.doi.org/10.1590/S1678-9946202163049 Text en https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Milosavljevic, Milos N. Milosavljevic, Jovana Z. Kocovic, Aleksandar G. Stefanovic, Srdjan M. Jankovic, Slobodan M. Djesevic, Miralem Milentijevic, Milica N. Antimicrobial treatment of Corynebacterium striatum invasive infections: a systematic review |
title | Antimicrobial treatment of Corynebacterium striatum
invasive infections: a systematic review |
title_full | Antimicrobial treatment of Corynebacterium striatum
invasive infections: a systematic review |
title_fullStr | Antimicrobial treatment of Corynebacterium striatum
invasive infections: a systematic review |
title_full_unstemmed | Antimicrobial treatment of Corynebacterium striatum
invasive infections: a systematic review |
title_short | Antimicrobial treatment of Corynebacterium striatum
invasive infections: a systematic review |
title_sort | antimicrobial treatment of corynebacterium striatum
invasive infections: a systematic review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216692/ https://www.ncbi.nlm.nih.gov/pubmed/34161555 http://dx.doi.org/10.1590/S1678-9946202163049 |
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