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The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression
The transcription factor Snai1, a well-known regulator of epithelial-to-mesenchymal transition, has been implicated in early cardiac morphogenesis as well as in cardiac valve formation. However, a role for Snai1 in regulating other aspects of cardiac morphogenesis has not been reported. Using geneti...
Autores principales: | Gentile, Alessandra, Bensimon-Brito, Anabela, Priya, Rashmi, Maischein, Hans-Martin, Piesker, Janett, Guenther, Stefan, Gunawan, Felix, Stainier, Didier YR |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216718/ https://www.ncbi.nlm.nih.gov/pubmed/34152269 http://dx.doi.org/10.7554/eLife.66143 |
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