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Genistein Attenuates Isoflurane-Induced Neuroinflammation by Inhibiting TLR4-Mediated Microglial-Polarization in vivo and in vitro

BACKGROUND: Isoflurane, a widely used anesthetic in surgery, has been found to induce neurotoxicity. In parallel, genistein is thought to attenuate isoflurane-induced neurotoxicity, although underlying molecular mechanisms are still unclear. In this study, we studied the protective effects of genist...

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Detalles Bibliográficos
Autores principales:	Jiang, Tao, Xu, Shoucai, Shen, Yangyang, Xu, Yong, Li, Yuwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216758/ https://www.ncbi.nlm.nih.gov/pubmed/34168482 http://dx.doi.org/10.2147/JIR.S304336

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