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Computer-Aided Brain Tumor Diagnosis: Performance Evaluation of Deep Learner CNN Using Augmented Brain MRI

Brain tumor is a deadly neurological disease caused by an abnormal and uncontrollable growth of cells inside the brain or skull. The mortality ratio of patients suffering from this disease is growing gradually. Analysing Magnetic Resonance Images (MRIs) manually is inadequate for efficient and accur...

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Autores principales: Naseer, Asma, Yasir, Tahreem, Azhar, Arifah, Shakeel, Tanzeela, Zafar, Kashif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216815/
https://www.ncbi.nlm.nih.gov/pubmed/34234822
http://dx.doi.org/10.1155/2021/5513500
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author Naseer, Asma
Yasir, Tahreem
Azhar, Arifah
Shakeel, Tanzeela
Zafar, Kashif
author_facet Naseer, Asma
Yasir, Tahreem
Azhar, Arifah
Shakeel, Tanzeela
Zafar, Kashif
author_sort Naseer, Asma
collection PubMed
description Brain tumor is a deadly neurological disease caused by an abnormal and uncontrollable growth of cells inside the brain or skull. The mortality ratio of patients suffering from this disease is growing gradually. Analysing Magnetic Resonance Images (MRIs) manually is inadequate for efficient and accurate brain tumor diagnosis. An early diagnosis of the disease can activate a timely treatment consequently elevating the survival ratio of the patients. Modern brain imaging methodologies have augmented the detection ratio of brain tumor. In the past few years, a lot of research has been carried out for computer-aided diagnosis of human brain tumor to achieve 100% diagnosis accuracy. The focus of this research is on early diagnosis of brain tumor via Convolution Neural Network (CNN) to enhance state-of-the-art diagnosis accuracy. The proposed CNN is trained on a benchmark dataset, BR35H, containing brain tumor MRIs. The performance and sustainability of the model is evaluated on six different datasets, i.e., BMI-I, BTI, BMI-II, BTS, BMI-III, and BD-BT. To improve the performance of the model and to make it sustainable for totally unseen data, different geometric data augmentation techniques, along with statistical standardization, are employed. The proposed CNN-based CAD system for brain tumor diagnosis performs better than other systems by achieving an average accuracy of around 98.8% and a specificity of around 0.99. It also reveals 100% correct diagnosis for two brain MRI datasets, i.e., BTS and BD-BT. The performance of the proposed system is also compared with the other existing systems, and the analysis reveals that the proposed system outperforms all of them.
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spelling pubmed-82168152021-07-06 Computer-Aided Brain Tumor Diagnosis: Performance Evaluation of Deep Learner CNN Using Augmented Brain MRI Naseer, Asma Yasir, Tahreem Azhar, Arifah Shakeel, Tanzeela Zafar, Kashif Int J Biomed Imaging Research Article Brain tumor is a deadly neurological disease caused by an abnormal and uncontrollable growth of cells inside the brain or skull. The mortality ratio of patients suffering from this disease is growing gradually. Analysing Magnetic Resonance Images (MRIs) manually is inadequate for efficient and accurate brain tumor diagnosis. An early diagnosis of the disease can activate a timely treatment consequently elevating the survival ratio of the patients. Modern brain imaging methodologies have augmented the detection ratio of brain tumor. In the past few years, a lot of research has been carried out for computer-aided diagnosis of human brain tumor to achieve 100% diagnosis accuracy. The focus of this research is on early diagnosis of brain tumor via Convolution Neural Network (CNN) to enhance state-of-the-art diagnosis accuracy. The proposed CNN is trained on a benchmark dataset, BR35H, containing brain tumor MRIs. The performance and sustainability of the model is evaluated on six different datasets, i.e., BMI-I, BTI, BMI-II, BTS, BMI-III, and BD-BT. To improve the performance of the model and to make it sustainable for totally unseen data, different geometric data augmentation techniques, along with statistical standardization, are employed. The proposed CNN-based CAD system for brain tumor diagnosis performs better than other systems by achieving an average accuracy of around 98.8% and a specificity of around 0.99. It also reveals 100% correct diagnosis for two brain MRI datasets, i.e., BTS and BD-BT. The performance of the proposed system is also compared with the other existing systems, and the analysis reveals that the proposed system outperforms all of them. Hindawi 2021-06-13 /pmc/articles/PMC8216815/ /pubmed/34234822 http://dx.doi.org/10.1155/2021/5513500 Text en Copyright © 2021 Asma Naseer et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Naseer, Asma
Yasir, Tahreem
Azhar, Arifah
Shakeel, Tanzeela
Zafar, Kashif
Computer-Aided Brain Tumor Diagnosis: Performance Evaluation of Deep Learner CNN Using Augmented Brain MRI
title Computer-Aided Brain Tumor Diagnosis: Performance Evaluation of Deep Learner CNN Using Augmented Brain MRI
title_full Computer-Aided Brain Tumor Diagnosis: Performance Evaluation of Deep Learner CNN Using Augmented Brain MRI
title_fullStr Computer-Aided Brain Tumor Diagnosis: Performance Evaluation of Deep Learner CNN Using Augmented Brain MRI
title_full_unstemmed Computer-Aided Brain Tumor Diagnosis: Performance Evaluation of Deep Learner CNN Using Augmented Brain MRI
title_short Computer-Aided Brain Tumor Diagnosis: Performance Evaluation of Deep Learner CNN Using Augmented Brain MRI
title_sort computer-aided brain tumor diagnosis: performance evaluation of deep learner cnn using augmented brain mri
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216815/
https://www.ncbi.nlm.nih.gov/pubmed/34234822
http://dx.doi.org/10.1155/2021/5513500
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