Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential

Pathology consisting of intracellular aggregates of alpha-Synuclein (α-Syn) spread through the nervous system in a variety of neurodegenerative disorders including Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy. The discovery of structurally distinct α-Syn polymorphs, so...

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Detalles Bibliográficos
Autores principales: Ferreira, Nelson, Gram, Hjalte, Sorrentino, Zachary A., Gregersen, Emil, Schmidt, Sissel Ida, Reimer, Lasse, Betzer, Cristine, Perez-Gozalbo, Clara, Beltoja, Marjo, Nagaraj, Madhu, Wang, Jie, Nowak, Jan S., Dong, Mingdong, Willén, Katarina, Cholak, Ersoy, Bjerregaard-Andersen, Kaare, Mendez, Nicolas, Rabadia, Prakruti, Shahnawaz, Mohammad, Soto, Claudio, Otzen, Daniel E., Akbey, Ümit, Meyer, Morten, Giasson, Benoit I., Romero-Ramos, Marina, Jensen, Poul Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217051/
https://www.ncbi.nlm.nih.gov/pubmed/33978813
http://dx.doi.org/10.1007/s00401-021-02316-0

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